{"product_id":"human-serine-threonine-protein-phosphatase-2b-catalytic-subunit-beta-isoform-ppp3cb-elisa-kit-bhe13703406","title":"Human Serine\/threonine-protein phosphatase 2B catalytic subunit beta isoform (PPP3CB) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Serine\/threonine-protein phosphatase 2B catalytic subunit beta isoform (PPP3CB) ELISA Kit has high sensitivity and excellent specificity for detection of Human PPP3CB. No significant cross-reactivity or interference between Human PPP3CB and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eCalcineurin, a calmodulin-regulated protein phosphatase, is found in the cells of all eukaryotes ranging from yeast to mammals. Wang et al. (1996) described this heterodimeric protein as having a 19-kD Ca(2+)-binding regulatory subunit, calcineurin B, and a 58- to 59-kD catalytic subunit, calcineurin A. One gene encodes calcineurin B (PPP3R1) in all tissues except testis, and it is highly conserved at the level of both protein and DNA sequences in eukaryotes. In contrast, there are 2 major isoforms, alpha (PPP3CA) and beta (PPP3CB), of calcineurin A encoded by separate genes located on different human chromosomes. A third isoform, A-gamma (PPP3CC), is unique to testis. Additional diversity of calcineurin A is created by alternative splicing of mRNAs.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338622984557,"sku":"KTE61190-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338792853869,"sku":"KTE61190-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338792886637,"sku":"KTE61190-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338792919405,"sku":"KTE61190-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE61190.png?v=1778954733","url":"https:\/\/www.ebiohippo.com\/products\/human-serine-threonine-protein-phosphatase-2b-catalytic-subunit-beta-isoform-ppp3cb-elisa-kit-bhe13703406","provider":"BioHippo","version":"1.0","type":"link"}