{"product_id":"human-sh3-domain-binding-protein-2-sh3bp2-elisa-kit-bhe13702885","title":"Human SH3 domain-binding protein 2 (SH3BP2) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman SH3 domain-binding protein 2 (SH3BP2) ELISA Kit has high sensitivity and excellent specificity for detection of Human SH3BP2. No significant cross-reactivity or interference between Human SH3BP2 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eSH3BP2 has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\u003cp\u003eThe deduced 561-residue protein contains an Src homology 2 (SH2) domain, an Src homology 3 (SH3)-binding domain, and a pleckstrin homology domain, suggesting a possible role in signal transduction.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338606469485,"sku":"KTE60669-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338740752749,"sku":"KTE60669-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338740785517,"sku":"KTE60669-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338740818285,"sku":"KTE60669-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60669.png?v=1778954683","url":"https:\/\/www.ebiohippo.com\/products\/human-sh3-domain-binding-protein-2-sh3bp2-elisa-kit-bhe13702885","provider":"BioHippo","version":"1.0","type":"link"}