{"product_id":"human-sialic-acid-binding-ig-like-lectin-10-siglec10-elisa-kit-bhe13702878","title":"Human Sialic acid-binding Ig-like lectin 10 (SIGLEC10) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Sialic acid-binding Ig-like lectin 10 (SIGLEC10) ELISA Kit has high sensitivity and excellent specificity for detection of Human SIGLEC10. No significant cross-reactivity or interference between Human SIGLEC10 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eBy searching an EST database for sequences resembling CD33 (SIGLEC3) and screening a spleen cDNA library, Munday et al. (2001) isolated a cDNA encoding SIGLEC10. Sequence analysis predicted that the 697-amino acid SIGLEC10 protein contains a signal peptide, an N-terminal V-set Ig-like domain and 4 C2-set Ig-like domains, 5 potential N-linked glycosylation sites, a transmembrane region, and a 126-residue cytoplasmic tail with 3 putative ITIMs. Northern blot analysis detected a major 3.0-kb SIGLEC10 transcript, with highest levels in spleen, lymph node, blood leukocytes, and appendix. Little or no expression was observed in pancreas, thyroid, and testis. Flow cytometric analysis demonstrated eosinophil-specific expression of SIGLEC10, but at a lower level than that of SIGLEC8.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338605453677,"sku":"KTE60662-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338740654445,"sku":"KTE60662-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338740687213,"sku":"KTE60662-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338740719981,"sku":"KTE60662-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60662.png?v=1778954679","url":"https:\/\/www.ebiohippo.com\/products\/human-sialic-acid-binding-ig-like-lectin-10-siglec10-elisa-kit-bhe13702878","provider":"BioHippo","version":"1.0","type":"link"}