{"product_id":"human-sialic-acid-binding-ig-like-lectin-6-siglec6-elisa-kit-bhe13702877","title":"Human Sialic acid-binding Ig-like lectin 6 (SIGLEC6) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Sialic acid-binding Ig-like lectin 6 (SIGLEC6) ELISA Kit has high sensitivity and excellent specificity for detection of Human SIGLEC6. No significant cross-reactivity or interference between Human SIGLEC6 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eThe deduced 442-amino acid CD33L protein contains a signal peptide, an N-terminal Ig-like V-domain, and 2 adjacent Ig C2-like domains, followed by a transmembrane region and a cytoplasmic tail. Based on its predicted structure, the authors stated that CD33L belongs to the Ig superfamily and is likely a novel member of the sialoadhesin subfamily. Compared to the original cDNA, this cDNA contains a 176-bp deletion in the coding sequence, resulting in a predicted 342-amino acid protein lacking the transmembrane and cytoplasmic regions. By RT-PCR of placenta RNA, the authors detected both transcripts, although the transcript encoding the membrane-bound isoform, CD33L1, was considerably more abundant.CD33L expression only in the placenta; transcripts of 4 distinct sizes were found, including 1 that was differentially polyadenylated.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338605519213,"sku":"KTE60661-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338740556141,"sku":"KTE60661-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338740588909,"sku":"KTE60661-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338740621677,"sku":"KTE60661-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60661.png?v=1778954681","url":"https:\/\/www.ebiohippo.com\/products\/human-sialic-acid-binding-ig-like-lectin-6-siglec6-elisa-kit-bhe13702877","provider":"BioHippo","version":"1.0","type":"link"}