{"product_id":"human-sodium-glucose-cotransporter-2-slc5a2-elisa-kit-bhe13702813","title":"Human Sodium\/glucose cotransporter 2 (SLC5A2) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Sodium\/glucose cotransporter 2 (SLC5A2) ELISA Kit has high sensitivity and excellent specificity for detection of Human SLC5A2. No significant cross-reactivity or interference between Human SLC5A2 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eThe major reabsorptive mechanism for D-glucose in the kidney is known to involve a lower affinity, high capacity Na(+)\/glucose cotransporter, which is located in the early proximal convoluted tubule segment S1 and has a Na(+)-to-glucose coupling ratio of 1:1.Uptake experiments using cRNA-injected Xenopus oocytes showed specific uptake of glucose and alpha-methyl glucopyranoside at up to three times background. This uptake was saturable, suggesting that the cDNA corresponds to a low-affinity kidney sodium-glucose transporter. It was therefore referred to as sodium-glucose cotransporter 2, or SGLT2. SGLT2 mediates saturable Na(+)-dependent and phlorizin-sensitive transport with K(m) values consistent with low affinity Na(+)\/glucose cotransport.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338604536173,"sku":"KTE60597-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338734395757,"sku":"KTE60597-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338734428525,"sku":"KTE60597-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338734461293,"sku":"KTE60597-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60597.png?v=1778954679","url":"https:\/\/www.ebiohippo.com\/products\/human-sodium-glucose-cotransporter-2-slc5a2-elisa-kit-bhe13702813","provider":"BioHippo","version":"1.0","type":"link"}