{"product_id":"human-soluble-receptor-activator-of-nuclear-factor-kb-srank-elisa-kit-bhe13702443","title":"Human Soluble Receptor Activator of Nuclear Factor-kB (sRANK) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Soluble Receptor Activator of Nuclear Factor-kB (sRANK) ELISA Kit has high sensitivity and excellent specificity for detection of Human TNFRSF11A. No significant cross-reactivity or interference between Human TNFRSF11A and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eSoluble Receptor Activator of Nuclear Factor-kB (sRANK) is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which sRANK induces the activation of NF-kappa B and MAPK8\/JNK. sRANKr and its ligand are important regulators of the interaction between T cells and dendritic cells. sRANK is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338592575853,"sku":"KTE60225-48T","price":359.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338696843629,"sku":"KTE60225-96T","price":619.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338696876397,"sku":"KTE60225-96TX5","price":2809.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338696909165,"sku":"KTE60225-96TX50","price":26209.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60225.png?v=1778954634","url":"https:\/\/www.ebiohippo.com\/products\/human-soluble-receptor-activator-of-nuclear-factor-kb-srank-elisa-kit-bhe13702443","provider":"BioHippo","version":"1.0","type":"link"}