{"product_id":"human-sonic-hedgehog-protein-shh-elisa-kit-bhe13702882","title":"Human Sonic hedgehog protein (SHH) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Sonic hedgehog protein (SHH) ELISA Kit has high sensitivity and excellent specificity for detection of Human SHH. No significant cross-reactivity or interference between Human SHH and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eSonic hedgehog (Shh) is a member of a small family of secreted proteins that are essential for development in both vertebrates and invertebrates. In mammals, there are three related hedgehog genes (sonic; desert; Indian) which share approximately 60 % amino acid (aa) identity. Human Shh is synthesized as a 437 aa precursor that contains a 24 aa signal sequence and a 413 aa mature region.\u003c\/p\u003e\u003cp\u003eThe mature region is autocatalytically processed into a nonglycosylated, 20 kDa, 174 aa N-terminal fragment (Shh-N), and a catalytic-processing, glycosylated, 34 kDa, 239 aa C-terminal fragment.The 20 kDa Shh-N fragment is the core of the active hedgehog molecule. It begins with a Cys and ends with a Gly, and both amino acids are sites of lipid modification.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338606436717,"sku":"KTE60666-48T","price":359.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338741244269,"sku":"KTE60666-96T","price":619.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338741277037,"sku":"KTE60666-96TX5","price":2809.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338741309805,"sku":"KTE60666-96TX50","price":26209.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60666.png?v=1778954682","url":"https:\/\/www.ebiohippo.com\/products\/human-sonic-hedgehog-protein-shh-elisa-kit-bhe13702882","provider":"BioHippo","version":"1.0","type":"link"}