{"product_id":"human-sphingomyelin-phosphodiesterase-2-smpd2-elisa-kit-bhe13702782","title":"Human Sphingomyelin phosphodiesterase 2 (SMPD2) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Sphingomyelin phosphodiesterase 2 (SMPD2) ELISA Kit has high sensitivity and excellent specificity for detection of Human SMPD2. No significant cross-reactivity or interference between Human SMPD2 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eSMPD2 isa protein which was initially identified as a sphingomyelinase based on sequence similarity between bacterial sphingomyelinases and a yeast protein. Subsequent studies showed that its biological function is less likely to be as a sphingomyelinase and instead as a lysophospholipase.\u003c\/p\u003e\u003cp\u003eNeutral sphingomyelinase (N-SMase) activity was first described in fibroblasts from patients with Niemann-Pick disease – a lysosomal storage disease characterized by deficiencies in acid SMase . Subsequent study found that this enzyme was the product of a distinct gene, had an optimum pH of 7.4, was dependent on Mg2+ ions for activity, and was particularly enriched in brain .\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338602832237,"sku":"KTE60566-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338730660205,"sku":"KTE60566-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338730692973,"sku":"KTE60566-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338730725741,"sku":"KTE60566-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60566.png?v=1778954669","url":"https:\/\/www.ebiohippo.com\/products\/human-sphingomyelin-phosphodiesterase-2-smpd2-elisa-kit-bhe13702782","provider":"BioHippo","version":"1.0","type":"link"}