{"product_id":"human-stromelysin-3-st3-elisa-kit-bhe13703815","title":"Human Stromelysin-3 (ST3) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Stromelysin-3 (ST3) ELISA Kit has high sensitivity and excellent specificity for detection of Human MMP11. No significant cross-reactivity or interference between Human MMP11 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by ST3 is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338636943725,"sku":"KTE61600-48T","price":359.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338833158509,"sku":"KTE61600-96T","price":619.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338833191277,"sku":"KTE61600-96TX5","price":2809.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338833224045,"sku":"KTE61600-96TX50","price":26209.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE61600.png?v=1778954776","url":"https:\/\/www.ebiohippo.com\/products\/human-stromelysin-3-st3-elisa-kit-bhe13703815","provider":"BioHippo","version":"1.0","type":"link"}