{"product_id":"human-sulfatase-modifying-factor-1-sumf1-elisa-kit-bhe13702620","title":"Human Sulfatase-modifying factor 1 (SUMF1) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Sulfatase-modifying factor 1 (SUMF1) ELISA Kit has high sensitivity and excellent specificity for detection of Human SUMF1. No significant cross-reactivity or interference between Human SUMF1 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eSulfatases catalyze the hydrolysis of sulfate esters such as glycosaminoglycans, sulfolipids, and steroid sulfates. C-alpha-formylglycine (FGly), the catalytic residue in the active site of eukaryotic sulfatases, is posttranslationally generated from a cysteine by SUMF1, the FGly-generating enzyme (FGE), in the endoplasmic reticulum (ER).\u003c\/p\u003e\u003cp\u003eThe genetic defect of FGly formation caused by mutations in the SUMF1 gene results in multiple sulfatase deficiency (MSD), a lysosomal storage disorder (Roeser et al., 2006).Highly expressed in kidney, pancreas and liver. Detected at lower levels in leukocytes, lung, placenta, small intestine, skeletal muscle and heart.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338597884269,"sku":"KTE60403-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338716471661,"sku":"KTE60403-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338716504429,"sku":"KTE60403-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338716537197,"sku":"KTE60403-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60403.png?v=1778954653","url":"https:\/\/www.ebiohippo.com\/products\/human-sulfatase-modifying-factor-1-sumf1-elisa-kit-bhe13702620","provider":"BioHippo","version":"1.0","type":"link"}