{"product_id":"human-t-cell-immunoreceptor-with-ig-and-itim-domains-tigit-elisa-kit-bhe13704539","title":"Human T cell immunoreceptor with Ig and ITIM domains (TIGIT) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman T cell immunoreceptor with Ig and ITIM domains (TIGIT) ELISA Kit has high sensitivity and excellent specificity for detection of Human TIGIT. No significant cross-reactivity or interference between Human TIGIT and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eTIGIT encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.\u003c\/p\u003e\u003cp\u003eThe predicted 244-amino acid TIGIT protein has a single Ig domain, followed by a type I transmembrane domain and a single intracellular immunoreceptor tyrosine-based inhibitory motif. It shares 88%, 67%, and 58% amino acid identity with its rhesus, dog, and mouse homologs, respectively.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338645299565,"sku":"KTE62327-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338857406829,"sku":"KTE62327-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338857439597,"sku":"KTE62327-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338857472365,"sku":"KTE62327-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE62327.png?v=1778954796","url":"https:\/\/www.ebiohippo.com\/products\/human-t-cell-immunoreceptor-with-ig-and-itim-domains-tigit-elisa-kit-bhe13704539","provider":"BioHippo","version":"1.0","type":"link"}