{"product_id":"human-tafi-cpb2-elisa-kit-ez-set-diy-antibody-pairs-bhe21000027","title":"Human TAFI\/CPB2 ELISA Kit EZ-Set™ (DIY Antibody Pairs)","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e Carboxypeptidase B2, 3.4.17.20, Carboxypeptidase U, CPU, Plasma carboxypeptidase B, pCPB, Thrombin-activable fibrinolysis inhibitor, TAFI.\u003c\/p\u003e\u003cp\u003eHuman \u003cstrong\u003eTAFI\/CPB2\u003c\/strong\u003e (\u003cstrong\u003eCPB2\u003c\/strong\u003e) is an established target in many assay panels, supporting hypothesis testing across diverse biological systems. This target is frequently investigated in \u003cstrong\u003eCoagulation \u0026amp; Hemostasis\u003c\/strong\u003e research contexts. Proteases and extracellular matrix (ECM) components are central to tissue architecture and remodeling. In many experimental contexts, changes in ECM-related proteins reflect shifts in cell adhesion, migration, barrier integrity, or matrix turnover.\u003c\/p\u003e\u003ch2\u003eBiological function and remodeling context\u003c\/h2\u003e\u003cp\u003eMatrix remodeling is influenced by the balance between synthesis and degradation, often regulated by inflammatory cues, mechanical stress, and growth-factor signaling. Protease activity can unmask or release bioactive fragments, while altered ECM composition can feed back on cell behavior through mechanotransduction and receptor engagement.\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRemodeling readout:\u003c\/strong\u003e Quantification can support studies of fibrosis, wound repair, and invasion models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMicroenvironment state:\u003c\/strong\u003e Levels may reflect stromal activation, barrier disruption, or matrix turnover.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMechanistic linkage:\u003c\/strong\u003e Pairing with inflammatory and growth-factor markers can clarify drivers of remodeling.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eDisease and translational relevance\u003c\/h2\u003e\u003cp\u003eECM remodeling and protease regulation are frequently discussed in the literature across oncology, cardiovascular, pulmonary, and inflammatory disease models. Interpretation of abundance should consider whether the measured analyte represents pro-forms, active forms, or fragments, and whether binding partners in the matrix influence detectability.\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"5 plates\/kit","offer_id":52920802083181,"sku":"EZ1502","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/ez1502-ELISA-human-tafi-cpb2-ez-set-elisa-kit-diy-antibody-pairs_6f9ed917-26e1-44fd-8f64-96e881ee9f8a.png?v=1769077477","url":"https:\/\/www.ebiohippo.com\/products\/human-tafi-cpb2-elisa-kit-ez-set-diy-antibody-pairs-bhe21000027","provider":"BioHippo","version":"1.0","type":"link"}