{"product_id":"human-tar-dna-binding-protein-43-tardbp-tdp43-elisa-kit-bhe13702695","title":"Human TAR DNA-binding protein 43 (TARDBP\/TDP43) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman TAR DNA-binding protein 43 (TARDBP\/TDP43) ELISA Kit has high sensitivity and excellent specificity for detection of Human TARDBP. No significant cross-reactivity or interference between Human TARDBP and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. TAR DNA-binding protein 43 (TARDBP\/TDP43) is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, TARDBP\/TDP43 regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338600145261,"sku":"KTE60478-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338722795885,"sku":"KTE60478-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338722828653,"sku":"KTE60478-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338722861421,"sku":"KTE60478-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60478.png?v=1778954659","url":"https:\/\/www.ebiohippo.com\/products\/human-tar-dna-binding-protein-43-tardbp-tdp43-elisa-kit-bhe13702695","provider":"BioHippo","version":"1.0","type":"link"}