{"product_id":"human-tom1-like-protein-1-tom1l1-elisa-kit-bhe13702387","title":"Human TOM1-like protein 1 (TOM1L1) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman TOM1-like protein 1 (TOM1L1) ELISA Kit has high sensitivity and excellent specificity for detection of Human TOM1L1. No significant cross-reactivity or interference between Human TOM1L1 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eMice hypomorphic for Tom1l2 exhibited numerous infections and tumors compared to wild-type littermates. Associated with this increased risk for infection and tumor formation, apparently healthy Tom1l2 hypomorphs also had splenomegaly, elevated B- and T-cell counts, and an impaired humoral response, although at a reduced penetrance.\u003c\/p\u003e\u003cp\u003eFurthermore, cellular localization studies showed that a Tom1l2-GFP fusion protein colocalizes with Golgi compartments, supporting the role of Tom1l2 in cellular trafficking, while molecular modeling and bioinformatic analysis of Tom1l2 illustrated a structural basis for a functional role in trafficking. These results indicate a role for Tom1l2 in the immune response and possibly in tumor suppression.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338589626733,"sku":"KTE60168-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338691961197,"sku":"KTE60168-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338691993965,"sku":"KTE60168-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338692026733,"sku":"KTE60168-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.ebiohippo.com\/products\/human-tom1-like-protein-1-tom1l1-elisa-kit-bhe13702387","provider":"BioHippo","version":"1.0","type":"link"}