{"product_id":"human-transforming-protein-rhoa-rhoa-elisa-kit-bhe13703013","title":"Human Transforming protein RhoA (RHOA) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Transforming protein RhoA (RHOA) ELISA Kit has high sensitivity and excellent specificity for detection of Human RHOA. No significant cross-reactivity or interference between Human RHOA and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eRhoA is a small GTPase protein known to regulate the actin cytoskeleton in the formation of stress fibers. It acts upon two known effector proteins: ROCK1 and DIAPH1.\u003c\/p\u003e\u003cp\u003eRhoA is part of a larger family of related proteins known as the Ras superfamily; proteins involved in the regulation and timing of cell division.RhoA activates ROCK (RhoA kinase) which stimulates LIM kinase, which then stimulates Cofilin, which effectively re-organises the Actin cytoskeleton of the cell. In the case of neurons, activation of this pathway results in growth cone collapse, therefore inhibits the growth and repair of neural pathways and axons. Inhibition of this pathway by its various components usually results in some level of improved remyelination.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338611057005,"sku":"KTE60797-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338754023789,"sku":"KTE60797-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338754056557,"sku":"KTE60797-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338754089325,"sku":"KTE60797-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60797.png?v=1778954694","url":"https:\/\/www.ebiohippo.com\/products\/human-transforming-protein-rhoa-rhoa-elisa-kit-bhe13703013","provider":"BioHippo","version":"1.0","type":"link"}