{"product_id":"human-tyro-protein-tyrosine-kinase-binding-protein-tyrobp-elisa-kit-bhe13702327","title":"Human TYRO protein tyrosine kinase-binding protein (TYROBP) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman TYRO protein tyrosine kinase-binding protein (TYROBP) ELISA Kit has high sensitivity and excellent specificity for detection of Human TYROBP. No significant cross-reactivity or interference between Human TYROBP and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eTYROBP encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338587300205,"sku":"KTE60108-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338688618861,"sku":"KTE60108-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338688651629,"sku":"KTE60108-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338688684397,"sku":"KTE60108-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60108.png?v=1778954626","url":"https:\/\/www.ebiohippo.com\/products\/human-tyro-protein-tyrosine-kinase-binding-protein-tyrobp-elisa-kit-bhe13702327","provider":"BioHippo","version":"1.0","type":"link"}