{"product_id":"human-tyrosine-protein-kinase-lyn-lyn-elisa-kit-bhe13703979","title":"Human Tyrosine-protein kinase Lyn (LYN) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Tyrosine-protein kinase Lyn (LYN) ELISA Kit has high sensitivity and excellent specificity for detection of Human LYN. No significant cross-reactivity or interference between Human LYN and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eUsing a v-yes DNA as the probe, Yamanashi et al. (1987) screened a human cDNA library made from placental RNA and derived DNA clones representing a novel genetic locus termed LYN. Nucleotide sequencing showed that LYN encodes a novel tyrosine kinase. Northern hybridization analysis showed that a 3.2-kb LYN mRNA was expressed in a variety of tissues of the human fetus. The pattern of expression was different from those of related genes such as YES.The degranulation response was dependent on a rise in intracellular calcium that was inhibited in Lyn-deficient mast cells but intact in Fyn-deficient cells. Degranulation proceeded in Lyn -\/- cells due to increased activation and constitutive phosphorylation of the calcium-independent protein kinase C delta isoform (PRKCD).\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338642579821,"sku":"KTE61764-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338849050989,"sku":"KTE61764-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338849083757,"sku":"KTE61764-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338849116525,"sku":"KTE61764-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE61764.png?v=1778954790","url":"https:\/\/www.ebiohippo.com\/products\/human-tyrosine-protein-kinase-lyn-lyn-elisa-kit-bhe13703979","provider":"BioHippo","version":"1.0","type":"link"}