{"product_id":"human-uracil-dna-glycosylase-ung-elisa-kit-bhe13702306","title":"Human Uracil-DNA glycosylase (UNG) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Uracil-DNA glycosylase (UNG) ELISA Kit has high sensitivity and excellent specificity for detection of Human UNG. No significant cross-reactivity or interference between Human UNG and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eUNG encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the nuclear (UNG2) and mitochondrial (UNG1) isoforms of UNG result from alternative splicing and the use of alternative promoters. The UNG1 and UNG2 proteins contain different N-terminal sequences, but the downstream 269 amino acids are common and include a short region that binds replication protein A and a larger, compact catalytic domain.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338587464045,"sku":"KTE60087-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338683212141,"sku":"KTE60087-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338683244909,"sku":"KTE60087-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338683277677,"sku":"KTE60087-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60087.png?v=1778954622","url":"https:\/\/www.ebiohippo.com\/products\/human-uracil-dna-glycosylase-ung-elisa-kit-bhe13702306","provider":"BioHippo","version":"1.0","type":"link"}