{"product_id":"human-vinculin-vcl-elisa-kit-bhe13702285","title":"Human Vinculin (VCL) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Vinculin (VCL) ELISA Kit has high sensitivity and excellent specificity for detection of Human VCL. No significant cross-reactivity or interference between Human VCL and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eIn mammalian cells, vinculin is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. Its sequence is 20-30% homologous to α-catenin, which serves a similar function.\u003c\/p\u003e\u003cp\u003eVinculin is a 117 kDa cytoskeletal protein with 1066 amino acids. The protein contains an acidic N-terminal domain and a basic C-terminal domain separated by a proline-rich middle segment. Vinculin consists of a globular head domain that contains binding sites for talin and α-actinin as well as a tyrosine phosphorylation site, while the tail region contains binding sites for F-actin, paxillin and lipids.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338586382701,"sku":"KTE60066-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338684293485,"sku":"KTE60066-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338684326253,"sku":"KTE60066-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338684359021,"sku":"KTE60066-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60066.png?v=1778954609","url":"https:\/\/www.ebiohippo.com\/products\/human-vinculin-vcl-elisa-kit-bhe13702285","provider":"BioHippo","version":"1.0","type":"link"}