{"product_id":"il9-antibody-interleukin-9-bha17135842","title":"IL9 Antibody \/ Interleukin 9","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003eIL9 Antibody \/ Interleukin 9 is a anti-IL9 Rabbit antibody Recombinant Rabbit Monoclonal clone 31I10 supplied in Liquid format. Recommended for workflows such as Western blot (WB) with listed reactivity in Human.\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTarget:\u003c\/strong\u003e IL9\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntibody details:\u003c\/strong\u003e Rabbit, Recombinant Rabbit Monoclonal, clone 31I10, isotype Rabbit IgG\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Liquid\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eApplications (as listed):\u003c\/strong\u003e WB\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eBiological background\u003c\/h2\u003e\u003cdiv\u003eIL9 antibody detects Interleukin 9, encoded by the IL9 gene. Interleukin 9 is a cytokine produced primarily by T helper 9 cells, a subset of CD4 positive T lymphocytes, and is involved in regulating immune responses, inflammation, and hematopoiesis. IL9 antibody allows researchers to monitor the presence and distribution of this cytokine in immune tissues and disease models, providing insights into how IL9 contributes to protective immunity and pathological inflammation. This cytokine exerts pleiotropic effects on multiple cell types, including mast cells, B cells, epithelial cells, and hematopoietic progenitors.\u003cbr\u003e\u003cbr\u003eInterleukin 9 was originally described as a T cell growth factor but has since been shown to have wide ranging effects. It promotes mast cell proliferation and activation, enhances antibody production by B cells, and stimulates mucus secretion by airway epithelial cells. Studies with IL9 antibody have demonstrated that this cytokine plays a key role in allergic diseases such as asthma, where IL9 driven mast cell and epithelial responses contribute to airway hyperreactivity. It also has roles in anti parasitic immunity, supporting host defense against helminths by promoting mast cell and eosinophil activity.\u003cbr\u003e\u003cbr\u003eDysregulation of IL9 production has been associated with chronic inflammatory diseases, autoimmune disorders, and cancer. Elevated IL9 levels are observed in asthma, atopic dermatitis, and inflammatory bowel disease, where it contributes to persistent inflammation and tissue remodeling. In oncology, IL9 can have both tumor promoting and anti tumor effects depending on context. Some studies using IL9 antibody have shown that it enhances tumor growth by supporting survival of malignant cells, while others suggest it can stimulate anti tumor immune responses. This dual role makes IL9 a target of interest for immunotherapy research.\u003cbr\u003e\u003cbr\u003eIL9 antibody is commonly applied in ELISA, western blotting, immunohistochemistry, and flow cytometry. ELISA provides quantitative measurement of IL9 levels in serum and culture supernatants, while immunohistochemistry reveals tissue specific expression patterns. Flow cytometry with IL9 antibody enables detection of intracellular cytokine production in T helper subsets, offering insights into immune cell differentiation and function. These applications ensure that IL9 antibody remains versatile for both basic immunology and clinical research.\u003cbr\u003e\u003cbr\u003eBy supplying validated IL9 antibody reagents,\u003c\/div\u003e\u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eConnecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).\u003c\/li\u003e\n\u003cli\u003eConsidering isoforms and post-translational regulation when interpreting protein-level changes.\u003c\/li\u003e\n\u003cli\u003eComparing results across species and model systems with matched controls.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\u003cli\u003e\n\u003cstrong\u003eWestern blotting:\u003c\/strong\u003e compare relative abundance and activation-state changes across conditions.\u003c\/li\u003e\u003c\/ul\u003e\u003cp\u003eInterpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.\u003c\/p\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eSignal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.\u003c\/li\u003e\n\u003cli\u003eSpecies differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eAntibody notes:\u003c\/strong\u003e Monoclonal antibodies provide a defined epitope recognition profile that can support consistent comparisons across experiments.\u003c\/p\u003e\u003c!-- Sources (internal): - UniProt search — UniProt — https:\/\/www.uniprot.org\/uniprotkb?query=IL9 - NCBI Gene search — NCBI — https:\/\/www.ncbi.nlm.nih.gov\/gene\/?term=IL9 - Ensembl search — Ensembl — https:\/\/www.ensembl.org\/Multi\/Search\/Results?q=IL9 - Human Protein Atlas search — HPA — https:\/\/www.proteinatlas.org\/search\/IL9 - PubMed (review) — NLM — https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=IL9+review --\u003e","brand":"NSJ Bioreagents","offers":[{"title":"Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg\/ml BSA \/ 100 ul","offer_id":53047306617197,"sku":"FY12940","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/get_image_9d322d56-d95b-415a-940d-82b31bc08203.jpg?v=1772019366","url":"https:\/\/www.ebiohippo.com\/products\/il9-antibody-interleukin-9-bha17135842","provider":"BioHippo","version":"1.0","type":"link"}