{"product_id":"immortalized-mouse-olfactory-bulb-cells-obc13-bhc10900784","title":"Immortalized Mouse Olfactory Bulb Cells (OBC13)","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\n\u003cp\u003eThe olfactory bulb is located within the vertebrate forebrain, in which it functions to receive nerve endings\/input from the nasal cavity. The sense of smell is associated with the nerve tissues of the olfactory bulb.Immortalized Mouse Olfactory Bulb Cells (OBC13) is immortalized with non-replicating retrovirus carrying the avian Myc gene.\u003c\/p\u003e\n\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eModel identity:\u003c\/strong\u003e Immortalized Mouse Olfactory Bulb Cells (OBC13) is supplied as an immortalized cell line derived from Mouse brain.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGrowth properties:\u003c\/strong\u003e Adherent, flattened dendritic processes\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGrowth conditions:\u003c\/strong\u003e To be cultured in Poly-L-Lysine coated flasks (TM061). PriGrow III (TM003) + 10% FBS(Regular*) + 1% Penicillin\/Streptomycin Solution (G255), 37.0°C, 5% CO₂ *Do not heat-inactivate\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProduct format:\u003c\/strong\u003e Frozen, BSL-2\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThis cell-based model is generally used in neurobiology, differentiation, and cell signaling studies. Donor\/background information is available for contextual interpretation.\u003c\/p\u003e\n\u003ch2\u003eBiological background\u003c\/h2\u003e\n\u003cp\u003eIt is a sister derivative from the Immortalized Mouse Olfactory Bulb Cells (OBC1) (Cat. No. T0235). The cells exhibit GalC (a marker for oligodendroglial lineage) marker, but has the absence of NF (neurofilament marker). Voltage-dependent potassium channels are expressed as well. OBC13 cells have been shown to form tumors in animal models, hence has the ability to be tumorigenic. It is a valuable in vitro tool for studies relating to the functions and the biology of the olfactory bulb.The cells express resistance to 0.3 mg\/ml G418 (Cat. No.G271). Donor\/background information provided for this product: New born CD-1xC57BL\/6 mice.\u003c\/p\u003e\n\u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eCultured cell-line models remain central to in vitro studies of phenotype, signaling, and pathway regulation under controlled conditions.\u003c\/li\u003e\n\u003cli\u003eResearchers commonly compare morphology, growth rate, and marker expression across media formulations, treatments, or time courses.\u003c\/li\u003e\n\u003cli\u003eInterpretation is generally strengthened by using matched controls, consistent passage handling, and appropriate culture surfaces.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eCommon research applications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eNeurobiology-focused studies of growth state, differentiation-associated morphology, and cell signaling changes in culture.\u003c\/li\u003e\n\u003cli\u003eCell-based assays that compare experimental perturbations across defined media and substrate conditions.\u003c\/li\u003e\n\u003cli\u003ePhenotype tracking using morphology, marker expression, or reporter output where applicable.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eChanges in morphology, growth rate, viability, or reporter signal are typically interpreted together with passage history, culture matrix, and the specified growth conditions for the model.\u003c\/p\u003e\n\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eMorphology, doubling behavior, and reporter or marker output can shift with passage number, substrate choice, and medium composition; these variables should be recorded alongside experimental readouts.\u003c\/li\u003e\n\u003cli\u003eMatched controls such as parental cells, untreated cultures, or parallel cultures maintained under identical conditions help distinguish background effects from biology of interest.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eCulture and product details\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGrowth Conditions:\u003c\/strong\u003e To be cultured in Poly-L-Lysine coated flasks (TM061). PriGrow III (TM003) + 10% FBS(Regular*) + 1% Penicillin\/Streptomycin Solution (G255), 37.0°C, 5% CO₂ *Do not heat-inactivate\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSeeding Density (cells\/cm²):\u003c\/strong\u003e 2,500 - 20, 000\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Applied Biological Materials (abm) Inc.","offers":[{"title":"1x10\u003csup\u003e6\u003c\/sup\u003e cells \/ 1.0 ml","offer_id":53180509520237,"sku":"T0237","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/ZnyJHuGaIlez1DHKHVuEpqKT9tX6CW5LDLD1ms5c.png?v=1782151792","url":"https:\/\/www.ebiohippo.com\/products\/immortalized-mouse-olfactory-bulb-cells-obc13-bhc10900784","provider":"BioHippo","version":"1.0","type":"link"}