{"product_id":"jw-55-bhb20409813","title":"JW 55","description":"\u003cstyle\u003e\n.bhp-desc{font-size:16px;color:#1a1a1a;line-height:1.7}\n.bhp-desc h2{font-size:18px;font-weight:700;color:#003366;margin:24px 0 10px;padding-bottom:6px;border-bottom:2px solid #003366}\n.bhp-desc p{margin:0 0 12px}\n.bhp-desc .bhp-spec-table{width:100%;border-collapse:collapse;margin:12px 0 18px}\n.bhp-desc .bhp-spec-table th{width:36%;text-align:left;padding:8px 12px;background:#e8f0fb;color:#003366;font-weight:600;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-spec-table td{padding:8px 12px;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-warning-box{background:#fff8e6;border-left:4px solid #e6a817;padding:10px 14px;margin:10px 0 14px;border-radius:0 4px 4px 0}\n\u003c\/style\u003e\n\u003cdiv class=\"bhp-desc\"\u003e\n  \u003ch2\u003eCompound Overview\u003c\/h2\u003e\n  \u003cp\u003e\u003cstrong\u003eJW 55\u003c\/strong\u003e (CAS 664993-53-7) is a research-grade small molecule supplied by TargetMol.\u003c\/p\u003e\n  \u003cp\u003e\u003cstrong\u003eAlternative names:\u003c\/strong\u003e JW55\u003c\/p\u003e\n  \u003ch2\u003ePhysical Properties\u003c\/h2\u003e\n  \u003ctable class=\"bhp-spec-table\"\u003e\n    \u003ctr\u003e\n\u003cth\u003eCAS Number\u003c\/th\u003e\n\u003ctd\u003e664993-53-7\u003c\/td\u003e\n\u003c\/tr\u003e\n    \u003ctr\u003e\n\u003cth\u003eMolecular Formula\u003c\/th\u003e\n\u003ctd\u003eC25H26N2O5\u003c\/td\u003e\n\u003c\/tr\u003e\n    \u003ctr\u003e\n\u003cth\u003eMolecular Weight\u003c\/th\u003e\n\u003ctd\u003e434.48 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n    \u003ctr\u003e\n\u003cth\u003eSMILES\u003c\/th\u003e\n\u003ctd style=\"font-size:13px;word-break:break-all\"\u003eCOC1=CC=C(C=C1)C1(CNC(=O)C2=CC=C(NC(=O)C3=CC=CO3)C=C2)CCOCC1\u003c\/td\u003e\n\u003c\/tr\u003e\n    \u003ctr\u003e\n\u003cth\u003eForm\u003c\/th\u003e\n\u003ctd\u003eSolid\u003c\/td\u003e\n\u003c\/tr\u003e\n    \u003ctr\u003e\n\u003cth\u003eShipping\u003c\/th\u003e\n\u003ctd\u003eRoom Temperature (RT)\u003c\/td\u003e\n\u003c\/tr\u003e\n  \u003c\/table\u003e\n  \u003ch2\u003eBiological Activity\u003c\/h2\u003e\n  \u003cp\u003eJW 55 (JW55) is an effective and selective beta-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1\/2).\u003c\/p\u003e\n  \u003cp\u003e\u003cstrong\u003eTarget(s):\u003c\/strong\u003e PARP, Wnt\/beta-catenin\u003c\/p\u003e\n  \u003cp\u003e\u003cstrong\u003eSignaling pathway(s):\u003c\/strong\u003e Chromatin\/Epigenetic, Cytoskeletal Signaling, DNA Damage\/DNA Repair, Stem Cells\u003c\/p\u003e\n  \u003ch2\u003eSafety \u0026amp; Regulatory\u003c\/h2\u003e\n  \u003cdiv class=\"bhp-warning-box\"\u003e\n    \u003cp\u003e\u003cstrong\u003eFor Research Use Only (RUO).\u003c\/strong\u003e Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.\u003c\/p\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e","brand":"TargetMol","offers":[{"title":"1 mL x 10 mM (in DMSO)","offer_id":53327207039341,"sku":"T1807-1MLX10MM","price":29.0,"currency_code":"USD","in_stock":true},{"title":"10 mg","offer_id":53327606546797,"sku":"T1807-10MG","price":35.0,"currency_code":"USD","in_stock":true},{"title":"25 mg","offer_id":53327606579565,"sku":"T1807-25MG","price":73.0,"currency_code":"USD","in_stock":true},{"title":"50 mg","offer_id":53327606612333,"sku":"T1807-50MG","price":119.0,"currency_code":"USD","in_stock":true},{"title":"100 mg","offer_id":53327606645101,"sku":"T1807-100MG","price":197.0,"currency_code":"USD","in_stock":true},{"title":"200 mg","offer_id":53327606677869,"sku":"T1807-200MG","price":292.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/CgoaEGayGn6EU28HAAAAAEvkvrk022.png?v=1778722109","url":"https:\/\/www.ebiohippo.com\/products\/jw-55-bhb20409813","provider":"BioHippo","version":"1.0","type":"link"}