{"product_id":"kcnk3-antibody-biotin-conjugated-bha10532257","title":"KCNK3 Antibody, Biotin conjugated","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003eThis polyclonal anti-KCNK3 antibody raised in Rabbit, conjugated with Biotin, tested in ELISA. Designed to detect KCNK3 in Human for neuroscience research.\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmunogen:\u003c\/strong\u003e Recombinant Human Potassium channel subfamily K member 3 protein (278-379AA) — determines epitope; confirm sample prep compatibility.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHost (Rabbit):\u003c\/strong\u003e Requires anti-rabbit-IgG secondary matching isotype IgG.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePolyclonal:\u003c\/strong\u003e Multiple epitopes = robust signal; lot-to-lot variability — include controls.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIsotype (IgG):\u003c\/strong\u003e Match secondary, Protein A\/G, and isotype controls to IgG.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurification (Protein G purification):\u003c\/strong\u003e Enriches Ig classes; reduces non-specific background.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiotin:\u003c\/strong\u003e Streptavidin\/avidin amplification; block endogenous biotin in biotin-rich samples.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eBiological background\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eKCNK3\u003c\/strong\u003e (also: Acid sensitive potassium channel protein TASK 1, Acid sensitive potassium channel protein TASK, Acid-sensitive potassium channel protein TASK-1, Cardiac two pore background K(+) channel, cTBAK 1, K2p3.1, KCNK3, KCNK3_HUMAN, OAT1, Potassium channel subfamily K member 3, potassium channel, subfamily K, member 3, Potassium inwardly rectifying channel subfamily K member 3, PPH4, rTASK, TASK 1, TASK, TBAK1, TWIK related acid sensitive K+ channel, TWIK-related acid-sensitive K(+) channel 1, Two P domain potassium channel, Two pore K(+) channel KT3., Two pore K(+) channel KT3.1, Two pore potassium channel KT3.1) — studied in Human systems. Expression, localization, and PTMs vary across cell types and disease states. Consult UniProt, NCBI Gene, and primary literature for current KCNK3 annotation relevant to neuroscience.\u003c\/p\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\u003cli\u003e\n\u003cstrong\u003eELISA:\u003c\/strong\u003e Quantify soluble target; ensure samples within the linear detection range.\u003c\/li\u003e\u003c\/ul\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIsotype controls:\u003c\/strong\u003e IgG from Rabbit at equivalent concentration.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCross-reactivity:\u003c\/strong\u003e Polyclonal: validate with KO\/KD controls.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMatrix effects:\u003c\/strong\u003e Verify dilution linearity in your sample matrix.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReactivity:\u003c\/strong\u003e Confirmed for Human; extrapolation requires validation.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eThis product is a polyclonal antibody purified from rabbit antiserum.\u003c\/em\u003e\u003c\/p\u003e\u003c!-- Sources: UniProt, NCBI Gene, Cusabio, Human Protein Atlas, PubMed --\u003e","brand":"CUSABIO TECHONOLOGY LLC","offers":[{"title":"50 ug","offer_id":53241131237741,"sku":"CSB-PA012071LD01HU-50UG","price":166.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53241222332781,"sku":"CSB-PA012071LD01HU-100UG","price":299.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.ebiohippo.com\/products\/kcnk3-antibody-biotin-conjugated-bha10532257","provider":"BioHippo","version":"1.0","type":"link"}