{"product_id":"malondialdehyde-antibody-bha11905578","title":"MOLECULAR SIGNATURE® Malondialdehyde Antibody","description":"\u003cp\u003eMalondialdehyde (MDA) is a highly reactive, low-molecular-weight aldehyde and one of the most widely used biomarkers of oxidative stress due to its chemical stability and ease of detection. Formed as a byproduct of lipid peroxidation, MDA reflects oxidative damage to polyunsaturated fatty acids in cellular membranes—a process central to the pathology of neurodegenerative diseases.\u003c\/p\u003e\n\n\u003cp\u003eMDA exhibits a strong affinity for amino groups, forming adducts with free amino acids, proteins, and nucleic acids. These adducts can disrupt protein function and induce DNA cross-linking, contributing to mutagenesis and cellular dysfunction. Elevated MDA levels have been consistently observed in Alzheimer’s disease and other neurodegenerative conditions, as well as in systemic diseases such as diabetes and cancer.\u003c\/p\u003e\n\n\u003cp\u003eIn neuroscience research, MDA serves not only as a diagnostic and prognostic marker but also as a mechanistic link between oxidative stress and neuronal injury. Its quantification—commonly performed using the thiobarbituric acid reactive substances (TBARS) assay—provides valuable insights into the redox state of the brain and the efficacy of antioxidant therapies.\u003c\/p\u003e\n\n\u003cp\u003eGiven its dual role as both a biomarker and a mediator of oxidative damage, MDA is a critical target in neurodegenerative disease research. Understanding and mitigating MDA-associated toxicity may offer new avenues for therapeutic intervention in oxidative stress-driven neurological disorders.\u003c\/p\u003e","brand":"StressMarq Biosciences Inc.","offers":[{"title":"100 ug \/ Unconjugated","offer_id":53040792076653,"sku":"SMC-515D","price":417.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ ATTO 390","offer_id":53040855843181,"sku":"SMC-515D-A390","price":472.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ ATTO 488","offer_id":53040855875949,"sku":"SMC-515D-A488","price":471.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ ATTO 594","offer_id":53040855908717,"sku":"SMC-515D-A594","price":471.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ APC","offer_id":53040855941485,"sku":"SMC-515D-APC","price":470.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ BI","offer_id":53040855974253,"sku":"SMC-515D-BI","price":467.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ FITC","offer_id":53040856007021,"sku":"SMC-515D-FITC","price":462.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ HRP","offer_id":53040856039789,"sku":"SMC-515D-HRP","price":458.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ PCP","offer_id":53040856072557,"sku":"SMC-515D-PCP","price":470.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ RPE","offer_id":53040856105325,"sku":"SMC-515D-RPE","price":468.0,"currency_code":"USD","in_stock":true},{"title":"12 ug \/ Unconjugated","offer_id":53040856138093,"sku":"SMC-515S","price":45.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/SMC-515_Malondialdehyde_Antibody_11E3_IHC_Mouse_Kidney_1.png?v=1771832151","url":"https:\/\/www.ebiohippo.com\/products\/malondialdehyde-antibody-bha11905578","provider":"BioHippo","version":"1.0","type":"link"}