{"product_id":"mdbn-bhb11900130","title":"MDBN","description":"\u003cp\u003eMDBN is an irreversible inhibitor of the AAA-ATPase p97, also known as valosin-containing protein (VCP), with an IC50 below 10 µM. p97 plays a central role in protein homeostasis, including ER-associated degradation (ERAD), autophagy, and stress granule dynamics. Mutations in p97 are linked to neurodegenerative disorders such as inclusion body myopathy and frontotemporal dementia. MDBN offers a pharmacological approach to modulate p97 activity and investigate its role in neuronal proteostasis and neurodegeneration.\u003c\/p\u003e","brand":"StressMarq Biosciences Inc.","offers":[{"title":"100 mg","offer_id":53040943497581,"sku":"SIH-342-100MG","price":60.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/SIH-342_MDBN_Chemical_Structure.png?v=1771837627","url":"https:\/\/www.ebiohippo.com\/products\/mdbn-bhb11900130","provider":"BioHippo","version":"1.0","type":"link"}