{"product_id":"middle-eastern-respiratory-syndrome-corona-virus-like-particles-mers-cov-bhv20900040","title":"Middle Eastern Respiratory Syndrome Corona Virus-like particles (MERS-CoV)","description":"\u003cstyle\u003e\n.bhp-desc{font-size:16px;color:#1a1a1a;line-height:1.7}\n.bhp-desc h2{font-size:18px;font-weight:700;color:#003366;margin:24px 0 10px;padding-bottom:6px;border-bottom:2px solid #003366}\n.bhp-desc p{margin:0 0 12px}\n.bhp-desc .bhp-spec-table{width:100%;border-collapse:collapse;margin:12px 0 18px}\n.bhp-desc .bhp-spec-table th{width:36%;text-align:left;padding:8px 12px;background:#e8f0fb;color:#003366;font-weight:600;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-spec-table td{padding:8px 12px;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-warning-box{background:#fff8e6;border-left:4px solid #e6a817;padding:10px 14px;margin:10px 0 14px;border-radius:0 4px 4px 0}\n.bhp-desc .bhp-cat-pill{display:inline-block;background:#003366;color:#fff;border-radius:20px;padding:3px 12px;font-size:13px;margin-bottom:10px}\n\u003c\/style\u003e\n\u003cdiv class=\"bhp-desc\"\u003e\n\u003ch2\u003eScientific Background\u003c\/h2\u003e\n\u003cp\u003eMiddle East Respiratory Syndrome Coronavirus (MERS-CoV) is a betacoronavirus first identified in Saudi Arabia in 2012. With a case fatality rate of approximately 35%, MERS-CoV remains a significant public health concern and a pandemic threat. MERS-CoV uses dipeptidyl peptidase-4 (DPP4\/CD26) as its receptor, and the spike protein mediates viral entry. Safe, quantitative tools for studying MERS-CoV entry and evaluating anti-MERS countermeasures are essential for research and drug development.\u003c\/p\u003e\n\u003ch2\u003eProduct Description\u003c\/h2\u003e\n\u003cp\u003e\u003cspan class=\"bhp-cat-pill\"\u003eCoronavirus\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eThis Ha-MERS-CoV VLP is a hybrid alpha-pseudovirus assembled from all four MERS-CoV structural proteins (S, M, N, E) with an alphavirus-derived reporter RNA payload. Single-cycle, BSL-2 safe. Available with Firefly luciferase, GFP, or RFP reporter. 60X concentrated format.\u003c\/p\u003e\n\u003ch2\u003eProduct Specifications\u003c\/h2\u003e\n\u003ctable class=\"bhp-spec-table\"\u003e\n\u003ctr\u003e\n\u003cth\u003eCatalog Number\u003c\/th\u003e\n\u003ctd\u003e0569-PP-002\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eFull Name\u003c\/th\u003e\n\u003ctd\u003eMERS-CoV Virus-Like Particles (Ha-MERS-CoV), Wild Type\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eStructural Proteins\u003c\/th\u003e\n\u003ctd\u003eS (spike), M (membrane), N (nucleocapsid), E (envelope)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eReporter Payload\u003c\/th\u003e\n\u003ctd\u003eAlphavirus-derived self-replicating RNA encoding Firefly Luciferase, GFP, or RFP\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eParticle Type\u003c\/th\u003e\n\u003ctd\u003eSingle-cycle alpha-pseudovirus (BSL-2 safe)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eTarget Cells\u003c\/th\u003e\n\u003ctd\u003eDPP4\/CD26-expressing cells (e.g., Vero cells, HEK293T-DPP4)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eForm\u003c\/th\u003e\n\u003ctd\u003eLiquid\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eSize\u003c\/th\u003e\n\u003ctd\u003e60X Concentrated: 5 × 100 µL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eStorage\u003c\/th\u003e\n\u003ctd\u003e-80°C. Avoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eApplications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eScreening and quantification of anti-MERS-CoV neutralizing antibodies\u003c\/li\u003e\n\u003cli\u003eAnti-MERS-CoV drug and entry inhibitor screening\u003c\/li\u003e\n\u003cli\u003eIdentification of host co-factors for MERS-CoV entry\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSafety \u0026amp; Handling\u003c\/h2\u003e\n\u003cdiv class=\"bhp-warning-box\"\u003e\n\u003cstrong\u003eResearch Use Only (RUO).\u003c\/strong\u003e BSL-2 safe single-cycle pseudovirus. Not for human or veterinary use. Commercial use requires written approval from Integrated BioTherapeutics, LLC.\u003c\/div\u003e\n\u003c\/div\u003e","brand":"IBT Bioservices","offers":[{"title":"Luciferase \/ 60x Conc. 5 x 100uL","offer_id":53402776535405,"sku":"0569-PP-002-LUC-60X","price":1643.0,"currency_code":"USD","in_stock":true},{"title":"Luciferase \/ 1x Conc. 25 x 200uL (~100 wells)","offer_id":53402776568173,"sku":"0569-PP-002-LUC-1X","price":2591.0,"currency_code":"USD","in_stock":true},{"title":"GFP \/ 60x Conc. 5 x 100uL","offer_id":53402776600941,"sku":"0569-PP-002-GFP-60X","price":1643.0,"currency_code":"USD","in_stock":true},{"title":"GFP \/ 1x Conc. 25 x 200uL (~100 wells)","offer_id":53402776633709,"sku":"0569-PP-002-GFP-1X","price":2591.0,"currency_code":"USD","in_stock":true},{"title":"RFP \/ 60x Conc. 5 x 100uL","offer_id":53402776666477,"sku":"0569-PP-002-RFP-60X","price":1643.0,"currency_code":"USD","in_stock":true},{"title":"RFP \/ 1x Conc. 25 x 200uL (~100 wells)","offer_id":53402776699245,"sku":"0569-PP-002-RFP-1X","price":2591.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Group-2106_a59007d8-a3a0-458d-8205-c5740b139089.png?v=1780516436","url":"https:\/\/www.ebiohippo.com\/products\/middle-eastern-respiratory-syndrome-corona-virus-like-particles-mers-cov-bhv20900040","provider":"BioHippo","version":"1.0","type":"link"}