{"product_id":"minpp1-antibody-multiple-inositol-polyphosphate-phosphatase-1-bha17135141","title":"MINPP1 Antibody \/ Multiple inositol polyphosphate phosphatase 1","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003eMINPP1 Antibody \/ Multiple inositol polyphosphate phosphatase 1 is an antibody targeting \u003cstrong\u003eMINPP1\u003c\/strong\u003e. Host: \u003cstrong\u003eRabbit\u003c\/strong\u003e. Polyclonal. Format: Lyophilized. Applications: WB, IHC, FACS, ELISA.\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTarget:\u003c\/strong\u003e MINPP1.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmunogen:\u003c\/strong\u003e E.coli-derived human MINPP1 recombinant protein (Position: R155-H421) was used as the immunogen for the MINPP1 antibody..\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpecies reactivity:\u003c\/strong\u003e Human, Mouse, Rat.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConjugate:\u003c\/strong\u003e Unconjugated (no label listed).\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eBiological background (from provided description)\u003c\/h2\u003e\u003cp\u003eMINPP1 antibody detects Multiple inositol polyphosphate phosphatase 1, encoded by the MINPP1 gene on chromosome 10q23.31. MINPP1 antibody is used in studies of inositol phosphate metabolism, signaling, and cancer biology. MINPP1 is a phosphatase localized to the endoplasmic reticulum (ER) lumen that dephosphorylates higher-order inositol polyphosphates, including IP4, IP5, and IP6, generating lower-phosphate species.\u003c\/p\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eWB:\u003c\/strong\u003e relative abundance and band pattern assessment using appropriate controls.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIHC:\u003c\/strong\u003e tissue distribution assessment; interpret with matched controls.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eAccount for isoforms, paralogs, and post-translational modifications when interpreting signal.\u003c\/li\u003e\n\u003cli\u003eSupport specificity with biological controls (e.g., KO\/KD where available) and technical controls (e.g., secondary-only\/isotype).\u003c\/li\u003e\n\u003c\/ul\u003e\u003c!-- Sources (internal): - UniProt Knowledgebase (UniProt) – https:\/\/www.uniprot.org\/ - NCBI Gene (NIH\/NLM) – https:\/\/www.ncbi.nlm.nih.gov\/gene\/ - ZFIN – https:\/\/zfin.org\/ - Ensembl – https:\/\/www.ensembl.org\/ - Nature Methods (2015): A proposal for validation of antibodies – https:\/\/www.nature.com\/articles\/nmeth.3230 --\u003e","brand":"NSJ Bioreagents","offers":[{"title":"Adding 0.2 ml of distilled water will yield a concentration of 500 ug\/ml \/ 100 ug","offer_id":53046719709549,"sku":"FY12238","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/get_image_1d1d7c13-5408-4a30-adc7-da0229272b7a.jpg?v=1782237004","url":"https:\/\/www.ebiohippo.com\/products\/minpp1-antibody-multiple-inositol-polyphosphate-phosphatase-1-bha17135141","provider":"BioHippo","version":"1.0","type":"link"}