{"product_id":"mouse-hemoglobin-bhp10506174","title":"Mouse Hemoglobin","description":"\u003ch2\u003eOverview\u003c\/h2\u003e \u003cp\u003eNative mouse hemoglobin (HGB) is purified from Mouse erythrocytes and supplied as a research reagent. It is commonly used as a reference material in biochemical and analytical workflows, and to support interpretation when naturally occurring proteoforms (for example, glycosylation or other post‑translational modifications) may matter.\u003c\/p\u003e \u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e \u003cul\u003e \u003cli\u003e\n\u003cstrong\u003eNative-source preparation:\u003c\/strong\u003e Purified from a biological source, which can be useful when studying naturally occurring proteoforms and complex formation.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eMolecular form:\u003c\/strong\u003e Full length protein.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eClassification:\u003c\/strong\u003e Binding Protein\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt;95%(SDS-PAGE) (as reported).\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Liquid\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eCommon names \/ aliases:\u003c\/strong\u003e haemoglobin,Hb\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eThese elements help determine how the reagent behaves in binding, stability, or quantitative measurements, and how closely it reflects biology in the chosen model system.\u003c\/p\u003e \u003ch2\u003eBiological background\u003c\/h2\u003e \u003cp\u003eHemoglobin is a tetrameric heme protein in red blood cells that transports oxygen and carbon dioxide. Cooperative ligand binding and allosteric regulation make hemoglobin a foundational model for studying protein conformational dynamics and redox chemistry.\u003c\/p\u003e\u003cp\u003eHemoglobin is involved in oxygen transport from the lung to the various peripheral tissues. The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult Hemoglobin.\u003c\/p\u003e \u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e \u003cul\u003e \u003cli\u003eRed blood cell physiology and oxidative stress research linking hemoglobin chemistry to cellular homeostasis.\u003c\/li\u003e \u003cli\u003eBiophysical studies of allostery and cooperative binding as general principles of protein regulation.\u003c\/li\u003e \u003cli\u003eMethod development for hemoglobin quantification and variant\/oxidation-state profiling (RUO).\u003c\/li\u003e \u003c\/ul\u003e \u003ch2\u003eCommon research applications\u003c\/h2\u003e \u003cul\u003e \u003cli\u003eOxygen\/ligand-binding and allostery studies using a classic multi-subunit protein system.\u003c\/li\u003e \u003cli\u003eReference material in analytical assays measuring hemoglobin or heme-protein content.\u003c\/li\u003e \u003cli\u003eRedox and oxidative modification studies (e.g., methemoglobin formation) as interpretable biochemical readouts.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eUse changes in abundance, binding, or activity readouts as context-dependent signals. In many systems, differences may reflect regulation, compartment shifts, complex formation, or sample-matrix effects rather than a single direct mechanism.\u003c\/p\u003e \u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e \u003cul\u003e \u003cli\u003eHemoglobin exists in multiple oxidation and ligand-bound states; these can shift spectra and assay signals.\u003c\/li\u003e \u003cli\u003eSpecies and strain differences can affect sequence and regulatory behavior; match to your model organism.\u003c\/li\u003e \u003cli\u003eIn complex samples, hemolysis and handling can strongly impact apparent hemoglobin measurements.\u003c\/li\u003e \u003c\/ul\u003e \u003c!-- Sources (internal): - UniProt: https:\/\/www.uniprot.org\/uniprotkb?query=hemoglobin HGB - NCBI Gene: https:\/\/www.ncbi.nlm.nih.gov\/gene\/?term=hemoglobin HGB - PubMed: https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=hemoglobin HGB%20review --\u003e","brand":"CUSABIO TECHNOLOGY LLC","offers":[{"title":"1 g","offer_id":53052976136557,"sku":"CSB-NP004901m-1G","price":245.0,"currency_code":"USD","in_stock":true},{"title":"100 mg","offer_id":53052976169325,"sku":"CSB-NP004901m-100MG","price":30.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/CSB-NP004901m-SDS.jpg?v=1772166487","url":"https:\/\/www.ebiohippo.com\/products\/mouse-hemoglobin-bhp10506174","provider":"BioHippo","version":"1.0","type":"link"}