{"product_id":"mouse-histon-h2b-histon-h2b-elisa-kit-bhe10802856","title":"Mouse histon-H2b (histon-H2b) ELISA Kit","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003emouse histon-H2b (histon-H2b) (H2B)\u003c\/strong\u003e is a molecular target commonly studied in signal transduction, cancer, and cardiovascular research. Many proteins are studied as molecular readouts that can change with cellular state, tissue remodeling, or stress responses.\u003c\/p\u003e\u003ch2\u003eBiological role and mechanism\u003c\/h2\u003e\u003cp\u003eThe biological role of histon-H2b is typically understood in terms of its molecular category and interaction network. Depending on the model system, it may participate in cell–cell communication, intracellular signaling, enzymatic processing, or regulation of gene expression programs. Mechanistic interpretation is often strengthened by considering upstream regulators and downstream readouts rather than relying on a single marker.\u003c\/p\u003e\u003cp\u003eExpression and abundance of histon-H2b can vary by tissue, cell type, and physiological state. In many systems, levels are influenced by factors such as developmental stage, immune activation, metabolic status, and cellular stress. Because sample matrix and pre-analytical handling can affect measured concentrations, interpretation is typically strongest when experiments keep collection and processing consistent across groups.\u003c\/p\u003e\u003ch2\u003eNomenclature and related terms\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003ehiston-H2b (histon-H2b) (H2B)\u003c\/strong\u003e may also be referenced as \u003cstrong\u003eHistone H2B type 1-A\u003c\/strong\u003e, \u003cstrong\u003eHistone H2B, testis\u003c\/strong\u003e, and \u003cstrong\u003eTestis-specific histone H2B\u003c\/strong\u003e in the literature or in databases. When comparing results across studies, confirm that the reported analyte refers to the same molecule, species context, and molecular form (e.g., precursor vs mature protein, or soluble vs membrane-associated forms).\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eUnderstanding how histon-H2b relates to tumor microenvironment biology, cell proliferation and apoptosis, metastasis and invasion pathways, and angiogenesis and immune-oncology mechanisms in signal transduction, cancer, and cardiovascular research.\u003c\/li\u003e\n\u003cli\u003eInterpreting shifts in histon-H2b levels alongside other pathway components or complementary markers.\u003c\/li\u003e\n\u003cli\u003eConnecting molecular changes to phenotypes such as inflammation, remodeling, metabolism shifts, or cell-state transitions (context-dependent).\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eMolecular forms and interpretation\u003c\/h2\u003e\u003cp\u003eFor some targets, isoforms, proteolytic processing, or post-translational modifications (such as phosphorylation or glycosylation) can influence function and apparent abundance. If multiple molecular forms are expected in your model, align interpretation with the form most relevant to the biological question.\u003c\/p\u003e\u003ch2\u003eDisease and translational relevance\u003c\/h2\u003e\u003cp\u003ehiston-H2b has been investigated across diverse physiological and disease contexts, and changes in its abundance have been reported in areas aligned with signal transduction, cancer, and cardiovascular studies. These associations are interpreted as research findings rather than diagnostic or therapeutic claims, and they should be evaluated alongside model-specific covariates and study design.\u003c\/p\u003e","brand":"Fine Test","offers":[{"title":"96 T","offer_id":52974857814381,"sku":"EM1117-96T","price":520.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/elisa_ba352da5-ae53-439c-9097-d121dea8772d.jpg?v=1769597503","url":"https:\/\/www.ebiohippo.com\/products\/mouse-histon-h2b-histon-h2b-elisa-kit-bhe10802856","provider":"BioHippo","version":"1.0","type":"link"}