{"product_id":"mouse-promethin-tmem159-elisa-kit-bhe13705352","title":"Mouse Promethin (TMEM159) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eMouse Promethin (TMEM159) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse TMEM159. No significant cross-reactivity or interference between Mouse TMEM159 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eBy PCR of a human heart cDNA library, Yu et al. (2004) cloned TMEM159, which they called promethin. The deduced 161-amino acid protein shares 70% identity with mouse promethin. Northern blot analysis revealed high expression of a 1.8-kb transcript in heart and skeletal muscle, with weak expression in kidney, small intestine, lung, and liver. Immunofluorescence microscopy localized promethin in the cytosol of transfected human cell lines.\u003c\/p\u003e\u003cp\u003eUsing microarray analysis, Yu et al. (2004) found that promethin was among the genes upregulated in a mouse model of hepatic steatosis caused by Pparg overexpression on a Ppara -\/- background. Promethin expression was not upregulated in hepatic steatosis induced by fasting or choline deficiency.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338654769517,"sku":"KTE70192-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338885325165,"sku":"KTE70192-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338885357933,"sku":"KTE70192-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338885390701,"sku":"KTE70192-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE70192.png?v=1778954821","url":"https:\/\/www.ebiohippo.com\/products\/mouse-promethin-tmem159-elisa-kit-bhe13705352","provider":"BioHippo","version":"1.0","type":"link"}