{"product_id":"mouse-serine-palmitoyltransferase-2-sptlc2-elisa-kit-bhe13705411","title":"Mouse Serine palmitoyltransferase 2 (SPTLC2) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eMouse Serine palmitoyltransferase 2 (SPTLC2) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse SPTLC2. No significant cross-reactivity or interference between Mouse SPTLC2 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eSerine palmitoyltransferase (SPT; EC 2.3.1.50) is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine.\u003c\/p\u003e\u003cp\u003eSPTLC2encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the initial enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal 5'-phosphate dependent condensation of L-serine and palmitoyl CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. Alternatively spliced variants encoding different isoforms have been identified.The LCB2 cDNA encodes a protein of 562 amino acids that is more than 90% identical to the mouse protein.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338655687021,"sku":"KTE70251-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338891518317,"sku":"KTE70251-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338891551085,"sku":"KTE70251-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338891583853,"sku":"KTE70251-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE70251.png?v=1778954826","url":"https:\/\/www.ebiohippo.com\/products\/mouse-serine-palmitoyltransferase-2-sptlc2-elisa-kit-bhe13705411","provider":"BioHippo","version":"1.0","type":"link"}