{"product_id":"mouse-transmembrane-protein-9b-tmem9b-elisa-kit-bhe13705321","title":"Mouse Transmembrane protein 9B (TMEM9B) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eMouse Transmembrane protein 9B (TMEM9B) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse TMEM9B. No significant cross-reactivity or interference between Mouse TMEM9B and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eThe intracellular signaling pathway by which TNF induces its pleiotropic actions is well-characterized and includes unique components, as well as modules shared with other signaling pathways. TMEM9B as an important component of TNF signaling and which is a module shared with the IL-1β and Toll-like receptor (TLR) pathways. is a glycosylated protein localized in membranes of the lysosome and partially in early endosomes. The expression of TMEM9B is required for the production of proinflammatory cytokines induced by TNF, IL-1β, and TLR ligands, but not for apoptotic cell death triggered by TNF or Fas ligand. TMEM9B is essential in TNF activation of both the NF-κB and MAPK pathways.TMEM9B is a key component of inflammatory signaling pathways and suggest that endosomal or lysosomal compartments regulate these pathways.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338652770669,"sku":"KTE70161-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338881786221,"sku":"KTE70161-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338881818989,"sku":"KTE70161-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338881851757,"sku":"KTE70161-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE70161.png?v=1778954817","url":"https:\/\/www.ebiohippo.com\/products\/mouse-transmembrane-protein-9b-tmem9b-elisa-kit-bhe13705321","provider":"BioHippo","version":"1.0","type":"link"}