{"product_id":"mouse-transportin-3-tnpo3-elisa-kit-bhe13705253","title":"Mouse Transportin-3 (TNPO3) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eMouse Transportin-3 (TNPO3) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse TNPO3. No significant cross-reactivity or interference between Mouse TNPO3 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eTNPO3 is a nuclear import receptor for serine\/arginine-rich (SR) proteins, which are essential precursor-mRNA splicing factors.By yeast 2-hybrid analysis using the RS domain of the E2 protein of human papillomavirus (HPV)-5 as bait, Lai et al. (2000) cloned a TNPO3 splice variant, TRNSR2, from a HeLa cell cDNA library. The deduced 923-amino acid TRNSR2 protein lacks 2 regions of about 30 amino acids each found in the TRNSR protein identified by Kataoka et al. (1999). Northern blot analysis detected ubiquitous expression of a 4.5-kb transcript, with highest expression in testis. Epitope-tagged TRNSR2 localized throughout transfected HeLa cells, but a mutant lacking the N-terminal region colocalized with splicing factor SC35 (SFRS2) in nuclear speckles.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338650411373,"sku":"KTE70091-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338875593069,"sku":"KTE70091-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338875625837,"sku":"KTE70091-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338875658605,"sku":"KTE70091-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE70091.png?v=1778954811","url":"https:\/\/www.ebiohippo.com\/products\/mouse-transportin-3-tnpo3-elisa-kit-bhe13705253","provider":"BioHippo","version":"1.0","type":"link"}