{"product_id":"mouse-tumor-associated-fibroblasts-hu-colon-cancer-origin-hct116-bhc16400294","title":"Mouse Tumor-Associated Fibroblasts (Hu. Colon Cancer Origin, HCT116)","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003eMouse Tumor-Associated Fibroblasts (Hu. Colon Cancer Origin, HCT116) are primary tumor-associated cells derived from mouse digestive-cell source colon cancer , hct116 context. Product metadata indicate an in vitro culture model and a reported BSL-2 handling context. Depending on the selected variant, the product may be supplied in selectable cryopreserved and flask formats (Frozen Vial (0.5 x 10^6 cells), T25 Flask, and T75 Flask) for in vitro studies that benefit from tissue-relevant cellular context.\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eSource and identity reflect the stated cells model and tissue origin, supporting experiments where digestive context matters.\u003c\/li\u003e\n\u003cli\u003eReported classifications and phenotype descriptors include primary, tumor-associated and disease context: Colon Cancer , HCT116.\u003c\/li\u003e\n\u003cli\u003eSelectable variants can include Frozen Vial (0.5 x 10^6 cells), T25 Flask, and T75 Flask; choose the listed format according to culture scale, handling preference, and downstream assay design.\u003c\/li\u003e\n\u003cli\u003eHandling considerations should follow institutional practice appropriate for the reported BSL-2 classification and the datasheet associated with the selected format.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eReview the specification table and variant selector together when choosing the appropriate format for assay scale, tissue context, and downstream readouts.\u003c\/p\u003e\u003ch2\u003eBiological background\u003c\/h2\u003e\u003cp\u003eThis cell model supports in vitro studies where tissue context, donor source, growth state, and phenotype-associated readouts are important for experimental interpretation. In this case, the stated source material and digestive context can influence morphology, baseline signaling, and assay responsiveness. The listed disease context (Colon Cancer , HCT116) may also be relevant when comparing baseline phenotype or response profiles.\u003c\/p\u003e\u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eCancer remains an active area for experiments that compare tissue-specific phenotype, pathway response, or functional readouts in culture-based systems.\u003c\/li\u003e\n\u003cli\u003eMetabolism \u0026amp; toxicology remains an active area for experiments that compare tissue-specific phenotype, pathway response, or functional readouts in culture-based systems.\u003c\/li\u003e\n\u003cli\u003eMultiparametric readouts such as cell culture, cell-based assays, and protein analysis are commonly combined to connect morphology, phenotype, and pathway-level response.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eCell culture and condition-optimization studies to assess morphology, growth behavior, or baseline phenotype over time.\u003c\/li\u003e\n\u003cli\u003eCell-based assays to compare responses to cytokines, compounds, co-culture conditions, or genetic perturbations.\u003c\/li\u003e\n\u003cli\u003eProtein-level analyses to monitor phenotype-associated markers, pathway activation, or secreted factors.\u003c\/li\u003e\n\u003cli\u003eImaging-based workflows to track morphology, localization, marker expression, cell-cell interactions, or reporter-linked signal.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eChanges in morphology, marker expression, proliferation, migration, barrier properties, reporter activity, or secreted factors are typically interpreted alongside matched controls and the selected culture conditions.\u003c\/p\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003ePotential confounders include donor-to-donor variability, passage-dependent phenotypic drift, substrate effects, serum or media composition, and differences between cryopreserved and expansion-stage material.\u003c\/li\u003e\n\u003cli\u003eUse matched controls and confirm identity with morphology- and marker-based readouts suited to the stated cell type, tissue source, and downstream assay.\u003c\/li\u003e\n\u003cli\u003eTumor-associated or disease-context cell sources can help model microenvironment-linked phenotypes, but matched controls are important for interpretation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"display:none\"\u003eSKU:BHC16400294\u003c\/p\u003e","brand":"Cell Biologics Inc","offers":[{"title":"Frozen Vial (0.5 x 10^6 cells)","offer_id":53195790811501,"sku":"MC-6231h-FV-0.5M","price":510.0,"currency_code":"USD","in_stock":true},{"title":"T25 Flask","offer_id":53196068421997,"sku":"MC-6231h-T25","price":560.0,"currency_code":"USD","in_stock":true},{"title":"T75 Flask","offer_id":53196068454765,"sku":"MC-6231h-T75","price":890.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.ebiohippo.com\/products\/mouse-tumor-associated-fibroblasts-hu-colon-cancer-origin-hct116-bhc16400294","provider":"BioHippo","version":"1.0","type":"link"}