{"product_id":"mouse-tumor-necrosis-factor-receptor-superfamily-member-10b-tnfrsf10b-elisa-kit-bhe13705292","title":"Mouse Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eMouse Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse TNFRSF10B. No significant cross-reactivity or interference between Mouse TNFRSF10B and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eTRAIL is a member of the tumor necrosis factor (TNF) family of cytokines and induces apoptosis in a wide variety of cells. Using a combination of PCR and library screening, the authors isolated cDNAs corresponding to the TRAILR2 coding region. The predicted 440-amino acid protein contains a putative signal peptide, 2 cysteine-rich pseudorepeats characteristic of TNF receptor (TNFR) family members, a transmembrane domain, and an intracellular death domain. The death domain of TRAILR2 shares 30% identity with that of TNFR1. Overall, the TRAIL receptors TRAILR2 and TRAILR1 (DR4) are 58% identical. Northern blot analysis indicated that TRAILR2 was expressed as a 4.4-kb mRNA in all tissues tested, with the highest levels of expression in peripheral blood lymphocytes, spleen, and ovary.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338651689325,"sku":"KTE70131-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338879033709,"sku":"KTE70131-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338879066477,"sku":"KTE70131-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338879099245,"sku":"KTE70131-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.ebiohippo.com\/products\/mouse-tumor-necrosis-factor-receptor-superfamily-member-10b-tnfrsf10b-elisa-kit-bhe13705292","provider":"BioHippo","version":"1.0","type":"link"}