{"product_id":"mouse-tumor-necrosis-factor-related-apoptosis-inducing-ligand-receptor-1-trail-r1-elisa-kit-bhe13705222","title":"Mouse Tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eMouse Tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse TRAILR1. No significant cross-reactivity or interference between Mouse TRAILR1 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.\u003c\/p\u003e\u003cp\u003ePan et al. (1997) found that, as with FAS, TNFR1, and DR3, overexpression of DR4 induced apoptosis. However, unlike the other 3 death receptors, DR4 did not use FADD  to transmit the death signal, suggesting the use of distinct proximal signaling machinery.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338649887085,"sku":"KTE70060-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338871923053,"sku":"KTE70060-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338871955821,"sku":"KTE70060-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338871988589,"sku":"KTE70060-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.ebiohippo.com\/products\/mouse-tumor-necrosis-factor-related-apoptosis-inducing-ligand-receptor-1-trail-r1-elisa-kit-bhe13705222","provider":"BioHippo","version":"1.0","type":"link"}