{"product_id":"ms4a14-antibody-membrane-spanning-4-domains-subfamily-a-member-14-bha17135771","title":"MS4A14 Antibody \/ Membrane spanning 4 domains subfamily A member 14","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003eMS4A14 Antibody \/ Membrane spanning 4 domains subfamily A member 14 is a anti-MS4A14 Rabbit antibody Recombinant Rabbit Monoclonal clone 29M80 supplied in Liquid format. Recommended for workflows such as Western blot (WB) with listed reactivity in Human.\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTarget:\u003c\/strong\u003e MS4A14\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntibody details:\u003c\/strong\u003e Rabbit, Recombinant Rabbit Monoclonal, clone 29M80, isotype Rabbit IgG\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Liquid\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eApplications (as listed):\u003c\/strong\u003e WB\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eBiological background\u003c\/h2\u003e\u003cdiv\u003eMS4A14 antibody detects membrane spanning 4 domains subfamily A member 14, a protein encoded by the MS4A14 gene. The MS4A family consists of transmembrane proteins characterized by four hydrophobic domains and is associated with immune signaling, membrane transport, and cell communication. MS4A14 antibody allows researchers to examine this less studied family member, providing insight into its biological functions and disease associations.\u003cbr\u003e\u003cbr\u003eAlthough the specific role of MS4A14 remains under investigation, proteins in the MS4A family are often involved in immune cell activation, receptor signaling, and calcium flux regulation. Several MS4A proteins, including MS4A1 (CD20), have well characterized roles in immune function and are targeted in therapeutic antibody development. MS4A14 antibody helps extend this research to uncover potential similarities in structure and function within the family.\u003cbr\u003e\u003cbr\u003eMS4A14 expression has been observed in various tissues, with elevated levels reported in certain cancers. Gene expression analyses suggest MS4A14 may contribute to tumor biology, making MS4A14 antibody useful for cancer biomarker discovery and validation. In addition, large scale genomic studies have linked MS4A family members to neurological conditions, including Alzheimer disease, highlighting potential roles in neural signaling and degeneration.\u003cbr\u003e\u003cbr\u003eMS4A14 antibody is commonly used in western blotting, immunohistochemistry, and flow cytometry. These applications reveal protein abundance, cellular localization, and surface expression patterns. Such approaches aid in clarifying whether MS4A14 functions in immune regulation, neurological processes, or oncogenic pathways.\u003cbr\u003e\u003cbr\u003eBy providing reagents such as MS4A14 antibody,\u003c\/div\u003e\u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eConnecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).\u003c\/li\u003e\n\u003cli\u003eConsidering isoforms and post-translational regulation when interpreting protein-level changes.\u003c\/li\u003e\n\u003cli\u003eComparing results across species and model systems with matched controls.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\u003cli\u003e\n\u003cstrong\u003eWestern blotting:\u003c\/strong\u003e compare relative abundance and activation-state changes across conditions.\u003c\/li\u003e\u003c\/ul\u003e\u003cp\u003eInterpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.\u003c\/p\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eSignal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.\u003c\/li\u003e\n\u003cli\u003eSpecies differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eAntibody notes:\u003c\/strong\u003e Monoclonal antibodies provide a defined epitope recognition profile that can support consistent comparisons across experiments.\u003c\/p\u003e\u003c!-- Sources (internal): - UniProt search — UniProt — https:\/\/www.uniprot.org\/uniprotkb?query=MS4A14 - NCBI Gene search — NCBI — https:\/\/www.ncbi.nlm.nih.gov\/gene\/?term=MS4A14 - Ensembl search — Ensembl — https:\/\/www.ensembl.org\/Multi\/Search\/Results?q=MS4A14 - Human Protein Atlas search — HPA — https:\/\/www.proteinatlas.org\/search\/MS4A14 - PubMed (review) — NLM — https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=MS4A14+review --\u003e","brand":"NSJ Bioreagents","offers":[{"title":"Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg\/ml BSA \/ 100 ul","offer_id":53047305666925,"sku":"FY12869","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/get_image_928d4b1d-c5bd-4010-9974-ab98d927359d.jpg?v=1772019356","url":"https:\/\/www.ebiohippo.com\/products\/ms4a14-antibody-membrane-spanning-4-domains-subfamily-a-member-14-bha17135771","provider":"BioHippo","version":"1.0","type":"link"}