{"product_id":"nipah-virus-like-particles-niv-bhv20900041","title":"Nipah Virus-like particles (NiV)","description":"\u003cstyle\u003e\n.bhp-desc{font-size:16px;color:#1a1a1a;line-height:1.7}\n.bhp-desc h2{font-size:18px;font-weight:700;color:#003366;margin:24px 0 10px;padding-bottom:6px;border-bottom:2px solid #003366}\n.bhp-desc p{margin:0 0 12px}\n.bhp-desc .bhp-spec-table{width:100%;border-collapse:collapse;margin:12px 0 18px}\n.bhp-desc .bhp-spec-table th{width:36%;text-align:left;padding:8px 12px;background:#e8f0fb;color:#003366;font-weight:600;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-spec-table td{padding:8px 12px;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-warning-box{background:#fff8e6;border-left:4px solid #e6a817;padding:10px 14px;margin:10px 0 14px;border-radius:0 4px 4px 0}\n.bhp-desc .bhp-cat-pill{display:inline-block;background:#003366;color:#fff;border-radius:20px;padding:3px 12px;font-size:13px;margin-bottom:10px}\n\u003c\/style\u003e\n\u003cdiv class=\"bhp-desc\"\u003e\n\u003ch2\u003eScientific Background\u003c\/h2\u003e\n\u003cp\u003eNipah Virus (NiV) is a highly pathogenic paramyxovirus (family Paramyxoviridae, genus Henipavirus) classified as a Biosafety Level 4 (BSL-4) agent and a WHO priority pathogen. NiV causes fatal encephalitis and respiratory disease in humans, with case fatality rates ranging from 40–75%. The virus uses ephrin B2 and B3 as cell entry receptors, mediated by the viral attachment glycoprotein (G) and fusion protein (F). Because work with live NiV requires BSL-4 containment, the development of safe surrogate systems is critical for medical countermeasure research.\u003c\/p\u003e\n\u003ch2\u003eProduct Description\u003c\/h2\u003e\n\u003cp\u003e\u003cspan class=\"bhp-cat-pill\"\u003eNipah Virus\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eThis HA-NiV is a novel rapid hybrid alpha-pseudovirus assembled from the four Nipah virus structural proteins (F, G, M, N) with an alphavirus-derived reporter RNA payload. BSL-2 safe and ready to use for viral entry studies. Reporter expression in target cells within 24 hours of transduction.\u003c\/p\u003e\n\u003ch2\u003eProduct Specifications\u003c\/h2\u003e\n\u003ctable class=\"bhp-spec-table\"\u003e\n\u003ctr\u003e\n\u003cth\u003eCatalog Number\u003c\/th\u003e\n\u003ctd\u003e0570-PP-001\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eFull Name\u003c\/th\u003e\n\u003ctd\u003eNipah Virus-like Particles (HA-NiV)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eStructural Proteins\u003c\/th\u003e\n\u003ctd\u003eF (fusion), G (glycoprotein\/attachment), M (matrix), N (nucleocapsid)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eReporter Payload\u003c\/th\u003e\n\u003ctd\u003eAlphavirus-derived self-replicating RNA encoding Firefly Luciferase, GFP, or RFP\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eParticle Type\u003c\/th\u003e\n\u003ctd\u003eSingle-cycle alpha-pseudovirus (BSL-2 safe)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eTarget Cells\u003c\/th\u003e\n\u003ctd\u003eEphrin B2\/B3-expressing cells (e.g., HEK293T)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eForm\u003c\/th\u003e\n\u003ctd\u003eLiquid\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eSize\u003c\/th\u003e\n\u003ctd\u003e1X Concentrated: 25 × 200 µL (~100 wells per 96-well plate)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eStorage\u003c\/th\u003e\n\u003ctd\u003e-80°C. Avoid repeated freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eApplications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eRapid NiV pseudovirus transduction of target cells for viral entry and functional studies\u003c\/li\u003e\n\u003cli\u003eAnti-NiV drug and entry inhibitor screening\u003c\/li\u003e\n\u003cli\u003eAnti-NiV neutralizing antibody screening and IC50 determination\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSafety \u0026amp; Handling\u003c\/h2\u003e\n\u003cdiv class=\"bhp-warning-box\"\u003e\n\u003cstrong\u003eResearch Use Only (RUO).\u003c\/strong\u003e Single-cycle BSL-2 safe pseudovirus. Does not contain replication-competent Nipah virus. Not for human or veterinary use. Commercial use requires written approval from Integrated BioTherapeutics, LLC.\u003c\/div\u003e\n\u003c\/div\u003e","brand":"IBT Bioservices","offers":[{"title":"Luciferase \/ 1x Conc. 25 x 200uL (~100 wells)","offer_id":53402775781741,"sku":"0570-PP-001-LUC-1X","price":4520.0,"currency_code":"USD","in_stock":true},{"title":"GFP \/ 1x Conc. 25 x 200uL (~100 wells)","offer_id":53402775814509,"sku":"0570-PP-001-GFP-1X","price":4520.0,"currency_code":"USD","in_stock":true},{"title":"RFP \/ 1x Conc. 25 x 200uL (~100 wells)","offer_id":53402775847277,"sku":"0570-PP-001-RFP-1X","price":4520.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/0570-PP-001.png?v=1780510315","url":"https:\/\/www.ebiohippo.com\/products\/nipah-virus-like-particles-niv-bhv20900041","provider":"BioHippo","version":"1.0","type":"link"}