{"product_id":"nitrotyrosine-elisa-kit-bhe11900023","title":"Nitrotyrosine ELISA Kit","description":"\u003cp\u003eNitrotyrosine is a stable biomarker formed by the nitration of tyrosine residues in proteins, typically through the action of reactive nitrogen species such as peroxynitrite. It serves as a reliable indicator of nitric oxide (NO)-dependent oxidative damage and chronic inflammation. Unlike transient NO metabolites, nitrotyrosine accumulates in tissues and circulates in the bloodstream, offering a longer-lasting signal of nitrosative stress.  In neuroscience, elevated nitrotyrosine levels have been detected in neuroinflammatory and neurodegenerative conditions, including Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis. Its presence reflects oxidative damage to neuronal proteins, disruption of cellular signaling, and mitochondrial dysfunction—hallmarks of progressive neurodegeneration.  Because protein-bound nitrotyrosine is more stable than free NO metabolites, it provides a more accurate measure of sustained oxidative injury in the brain. Its detection in cerebrospinal fluid and brain tissue supports its use as a diagnostic and prognostic biomarker in neurological research.\u003c\/p\u003e \u003cul\u003e   \u003cli\u003e\n\u003cstrong\u003ePlatform:\u003c\/strong\u003e Microplate\u003c\/li\u003e   \u003cli\u003e\n\u003cstrong\u003eIncubation Time:\u003c\/strong\u003e 1 hour\u003c\/li\u003e \u003c\/ul\u003e","brand":"StressMarq Biosciences Inc.","offers":[{"title":"96 well","offer_id":53047418585453,"sku":"SKT-126-96","price":448.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/SKT-126_Nitrotyrosine_ELISA_Kit_Standard_Curve.png?v=1772024679","url":"https:\/\/www.ebiohippo.com\/products\/nitrotyrosine-elisa-kit-bhe11900023","provider":"BioHippo","version":"1.0","type":"link"}