{"product_id":"p62-antibody-bha17101131","title":"p62 Antibody","description":"\u003cp\u003eSQSTM1\/p62 is an adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. This protein may play a role in titin\/TTN downstream signaling in muscle cells, and may also regulate signaling cascades through ubiquitination. This protein is involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. SQSTM1\/p62 also appears to play a role in macroautophagic removal of intracellular protein aggregates. Cellular depletion studies of SQSTM1\/p62 have indicated a role for association with LC3 and aggregate proteins in order to facilitate normal formation of the autophagosome.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Antigen affinity purified\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePredicted species reactivity:\u003c\/strong\u003e Mouse, Rat\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"NSJ Bioreagents","offers":[{"title":"In 1X PBS, pH 7.4, with 0.09% sodium azide \/ 0.08 ml","offer_id":53042890834285,"sku":"F48010-0.08ML","price":205.0,"currency_code":"USD","in_stock":true},{"title":"In 1X PBS, pH 7.4, with 0.09% sodium azide \/ 0.4 ml","offer_id":53042973311341,"sku":"F48010-0.4ML","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/get_image_b877e27e-e796-408e-be22-6d7e271bdc44.jpg?v=1771923798","url":"https:\/\/www.ebiohippo.com\/products\/p62-antibody-bha17101131","provider":"BioHippo","version":"1.0","type":"link"}