{"product_id":"phospho-ark-2-3-t236-202-polyclonal-antibody-bha12100038","title":"Phospho-ARK-2\/3 (T236\/202) Polyclonal Antibody","description":"\u003cstyle\u003e\n.bhp-desc{font-size:16px;color:#1a1a1a;line-height:1.7}\n.bhp-desc h2{font-size:18px;font-weight:700;color:#003366;margin:24px 0 10px;padding-bottom:6px;border-bottom:2px solid #003366}\n.bhp-desc p{margin:0 0 12px}\n.bhp-desc .bhp-spec-table{width:100%;border-collapse:collapse;margin:12px 0 18px}\n.bhp-desc .bhp-spec-table th{width:36%;text-align:left;padding:8px 12px;background:#e8f0fb;color:#003366;font-weight:600;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-spec-table td{padding:8px 12px;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-qc-badge{display:inline-block;background:#e6f4ea;color:#1a7a3c;border:1px solid #a8d5b5;border-radius:4px;padding:6px 14px;font-size:14px;font-weight:600}\n.bhp-desc .bhp-warning-box{background:#fff8e6;border-left:4px solid #e6a817;padding:10px 14px;margin:10px 0 14px;border-radius:0 4px 4px 0}\n.bhp-desc .bhp-cat-pill{display:inline-block;background:#003366;color:#fff;border-radius:20px;padding:3px 12px;font-size:13px;margin-bottom:10px}\n\u003c\/style\u003e\n\u003cdiv class=\"bhp-desc\"\u003e\n\u003ch2\u003eProduct Overview\u003c\/h2\u003e\n\u003cspan class=\"bhp-cat-pill\"\u003ePrimary Antibody\u003c\/span\u003e\n\u003cp\u003eThis antibody targets AURKB and detects endogenous levels of AURKB protein. Only detects the phosphorylated form of AURKB.\u003c\/p\u003e\n\n\u003ch2\u003eValidated Applications\u003c\/h2\u003e\n\u003ctable class=\"bhp-spec-table\"\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eApplication\u003c\/th\u003e\n\u003cth\u003eDilution Guidance\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eImmunohistochemistry (IHC)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eRefer to datasheet for recommended working dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eELISA\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eRefer to datasheet for recommended working dilution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cspan class=\"bhp-qc-badge\"\u003e✔ Validated by Bioassay Technology Laboratory\u003c\/span\u003e\n\n\u003ch2\u003eAntibody Specifications\u003c\/h2\u003e\n\u003ctable class=\"bhp-spec-table\"\u003e\n\u003ctr\u003e\n\u003cth\u003eTarget\u003c\/th\u003e\n\u003ctd\u003eAURKB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eHost\u003c\/th\u003e\n\u003ctd\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eClonality\u003c\/th\u003e\n\u003ctd\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eIsotype\u003c\/th\u003e\n\u003ctd\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eReactivity\u003c\/th\u003e\n\u003ctd\u003eHuman, Mouse, Rat\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003ePurification\u003c\/th\u003e\n\u003ctd\u003eAffinity Purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eMolecular Weight\u003c\/th\u003e\n\u003ctd\u003e~39.3\/~35.6 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eConcentration\u003c\/th\u003e\n\u003ctd\u003e1 mg\/ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eImmunogen\u003c\/th\u003e\n\u003ctd\u003eThe antiserum was produced against synthesized peptide derived from human AurB\/C around the phosphorylation site of Thr236\/202. AA range:201-250\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eFormulation\u003c\/th\u003e\n\u003ctd\u003eLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eStorage\u003c\/th\u003e\n\u003ctd\u003e-20°C for 1 year\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eGene ID\u003c\/th\u003e\n\u003ctd\u003eHuman: 9212\/6795; Mouse: 20877; Rat: 114592\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eUniProt\u003c\/th\u003e\n\u003ctd\u003e\n\u003ca href=\"https:\/\/www.uniprot.org\/uniprotkb\/Q96GD4\" target=\"_blank\" style=\"color:#003366\"\u003eQ96GD4\u003c\/a\u003e (Human: Q96GD4\/Q9UQB9; Rat: O55099)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\n\u003ch2\u003eScientific Background\u003c\/h2\u003e\n\u003cp\u003eAURKB (aurora kinase B) encodes a member of the aurora kinase subfamily of serine\/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of AURKB is located on chromosome 8. Alternatively spliced transcript variants have been found for AURKB.\u003c\/p\u003e\n\u003ch2\u003eAlternative Names\u003c\/h2\u003e\n\u003cp style=\"color:#555\"\u003eAURKB; AIK2; AIM1; AIRK2; ARK2; STK1; STK12; STK5; Aurora kinase B; Aurora 1; Aurora- and IPL1-like midbody-associated protein 1; AIM-1; Aurora\/IPL1-related kinase 2; ARK-2; Aurora-related kinase 2; S\u003c\/p\u003e\n\n\u003ch2\u003eSafety \u0026amp; Handling\u003c\/h2\u003e\n\u003cdiv class=\"bhp-warning-box\"\u003e\n\u003cstrong\u003e⚠ Research Use Only (RUO).\u003c\/strong\u003e Not approved for diagnostic or therapeutic use. Handle with standard laboratory safety precautions. Contains sodium azide — avoid contact with skin\/eyes; dispose per local regulations.\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Bioassay Technology Laboratory","offers":[{"title":"20 uL","offer_id":53327964111213,"sku":"BT-PHS01015-20UL","price":108.0,"currency_code":"USD","in_stock":true},{"title":"50 uL","offer_id":53327978070381,"sku":"BT-PHS01015-50UL","price":180.0,"currency_code":"USD","in_stock":true},{"title":"100 uL","offer_id":53327978103149,"sku":"BT-PHS01015-100UL","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/nopic1.jpg?v=1778728703","url":"https:\/\/www.ebiohippo.com\/products\/phospho-ark-2-3-t236-202-polyclonal-antibody-bha12100038","provider":"BioHippo","version":"1.0","type":"link"}