{"product_id":"pik3c2a-antibody-bha10806441","title":"PIK3C2A antibody","description":"\u003cdiv class=\"bhp-desc\"\u003e\n\u003cstyle\u003e\n.bhp-desc{font-size:16px;color:#1a1a1a;line-height:1.7}\n.bhp-desc h2{font-size:18px;font-weight:700;color:#003366;margin:24px 0 10px;padding-bottom:6px;border-bottom:2px solid #003366}\n.bhp-desc p{margin:0 0 12px}\n.bhp-desc ul{margin:0 0 12px;padding-left:22px}\n.bhp-desc .bhp-spec-table{width:100%;border-collapse:collapse;margin:12px 0 18px}\n.bhp-desc .bhp-spec-table th{width:36%;text-align:left;padding:8px 12px;background:#e8f0fb;color:#003366;font-weight:600;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-spec-table td{padding:8px 12px;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-warning-box{background:#fff8e6;border-left:4px solid #e6a817;padding:10px 14px;margin:10px 0 14px;border-radius:0 4px 4px 0}\n.bhp-desc .bhp-cat-pill{display:inline-block;background:#003366;color:#fff;border-radius:20px;padding:3px 12px;font-size:13px;margin-bottom:10px}\n\u003c\/style\u003e\n\n\u003ch2\u003eProduct Overview\u003c\/h2\u003e\n\u003cp\u003eThe protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling.\u003c\/p\u003e\n\u003cspan class=\"bhp-cat-pill\"\u003ePolyclonal Rabbit Antibody\u003c\/span\u003e\n\n\u003ch2\u003eValidated Applications\u003c\/h2\u003e\n\u003ctable class=\"bhp-spec-table\"\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eApplication\u003c\/th\u003e\n\u003cth\u003eRecommended Dilution\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eELISA\u003c\/td\u003e\n\u003ctd\u003eRefer to datasheet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWestern Blot\u003c\/td\u003e\n\u003ctd\u003eRefer to datasheet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImmunohistochemistry\u003c\/td\u003e\n\u003ctd\u003eRefer to datasheet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\n\u003ch2\u003eImmunogen \u0026amp; Specificity\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eImmunogen:\u003c\/strong\u003e phosphoinositide-3-kinase, class 2, alpha polypeptide\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUniProt\/Swiss-Prot:\u003c\/strong\u003e \u003ca href=\"https:\/\/www.uniprot.org\/uniprot\/O00443\" target=\"_blank\"\u003eO00443\u003c\/a\u003e\u003c\/p\u003e\n\n\u003ch2\u003eProduct Specifications\u003c\/h2\u003e\n\u003ctable class=\"bhp-spec-table\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eHost Species\u003c\/th\u003e\n\u003ctd\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eClonality\u003c\/th\u003e\n\u003ctd\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eIsotype\u003c\/th\u003e\n\u003ctd\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecies Reactivity\u003c\/th\u003e\n\u003ctd\u003eHuman, Mouse, Rat\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003ePurification Method\u003c\/th\u003e\n\u003ctd\u003eImmunogen Affinity Purified\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003ePurity\u003c\/th\u003e\n\u003ctd\u003e≥95% as determined by SDS-PAGE\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eMolecular Weight\u003c\/th\u003e\n\u003ctd\u003e191 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eStorage\u003c\/th\u003e\n\u003ctd\u003ePBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze \/ thaw cycles.)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\n\u003ch2\u003eReactivity Notes\u003c\/h2\u003e\n\u003cp\u003eConfirmed reactivity in \u003cstrong\u003eHuman, Mouse, Rat\u003c\/strong\u003e samples; validated for \u003cstrong\u003eELISA, Western Blot, Immunohistochemistry\u003c\/strong\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eSafety \u0026amp; Handling\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eFor Research Use Only (RUO). Not intended for diagnostic procedures.\u003c\/li\u003e\n\u003cli\u003eShipping: cold-chain shipment (typically with ice packs).\u003c\/li\u003e\n\u003cli\u003eUpon receipt: store at recommended temperature as soon as possible.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSales terms and conditions\u003c\/strong\u003e: Please review prior to ordering.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eRelated Products\u003c\/h2\u003e\n\u003cp\u003eExplore additional antibodies and related detection reagents for \u003cstrong\u003ePIK3C2A\u003c\/strong\u003e in the BioHippo catalog.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Fine Test","offers":[{"title":"100 ug","offer_id":53327790768493,"sku":"FNab06449-100UG","price":338.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/antibody_b8d879ee-d328-4eb1-8e48-e8727c6899ba.jpg?v=1778727719","url":"https:\/\/www.ebiohippo.com\/products\/pik3c2a-antibody-bha10806441","provider":"BioHippo","version":"1.0","type":"link"}