{"product_id":"ppm1g-human-bhz11000569","title":"PPM1G Human","description":"\u003cdiv class=\"bhp-desc\"\u003e\n\u003ch3 style=\"color:#1a5c58;margin:12px 0 4px\"\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eProtein Phosphatase 1G Human Recombinant\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"bhp-desc\"\u003e\n\u003ch3 style=\"color:#1a5c58;margin:12px 0 4px\"\u003eOverview\u003c\/h3\u003e\n\u003cp\u003ePPM1G is part of the PP2C family of Ser\/Thr protein phosphatases which are known to be negative regulators of cell stress response pathways. PPM1G is accountable for the dephosphorylation of Pre-mRNA splicing factors, an important factor for the formation of functional spliceosome. PPM1G regulates cell cycle progression. PPM1G mediates histone dephosphorylation\/exchange in response to DNA damage or checkpoint recovery in higher eukaryotes. The degradation of p21\/WAF1 induced by PPM1G is mediated in a proteasome-dependent manner. Protein phosphatase 1G regulates assembly and function of the beta-catenin degradation complex.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"bhp-desc\"\u003e\n\u003ch3 style=\"color:#1a5c58;margin:12px 0 4px\"\u003eSpecifications\u003c\/h3\u003e\n\u003ctable style=\"width:100%;border-collapse:collapse;font-size:0.92em\"\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align:left;padding:4px 8px;background:#e8f4f3;width:180px;font-weight:bold\"\u003ePurity\u003c\/th\u003e\n\u003ctd style=\"padding:4px 8px\"\u003eGreater than 95.0% as determined by SDS-PAGE.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align:left;padding:4px 8px;background:#e8f4f3;width:180px;font-weight:bold\"\u003eFormulation\u003c\/th\u003e\n\u003ctd style=\"padding:4px 8px\"\u003eThe PPM1G solution (1mg\/ml) contains 25mM Tris pH-7.5, 1mM DTT, 1mM EDTA, 2mM b-ME and 20% glycerol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align:left;padding:4px 8px;background:#e8f4f3;width:180px;font-weight:bold\"\u003eStorage\u003c\/th\u003e\n\u003ctd style=\"padding:4px 8px\"\u003eStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth style=\"text-align:left;padding:4px 8px;background:#e8f4f3;width:180px;font-weight:bold\"\u003eExpression System\u003c\/th\u003e\n\u003ctd style=\"padding:4px 8px\"\u003eEscherichia Coli.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"10µg","offer_id":53340129001837,"sku":"ENZ-368-10µg","price":60.0,"currency_code":"USD","in_stock":true},{"title":"50µg","offer_id":53340191752557,"sku":"ENZ-368-50µg","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":53340191785325,"sku":"ENZ-368-1mg","price":1800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ppm1g-human-ENZ-368.png?v=1782158448","url":"https:\/\/www.ebiohippo.com\/products\/ppm1g-human-bhz11000569","provider":"BioHippo","version":"1.0","type":"link"}