{"product_id":"primary-mouse-cd-1-hepatocytes-plateable-bhc10901833","title":"Primary Mouse (CD-1) Hepatocytes, Plateable","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003ePrimary Mouse (CD-1) Hepatocytes, Plateable, are freshly isolated hepatocytes from CD-1 mice, optimized for attachment and functional maintenance in vitro. These cells retain key liver-specific functions, including drug metabolism, protein synthesis, and enzymatic activity, making them ideal for studies in hepatotoxicity, drug screening, metabolism, liver disease modeling, and basic hepatic biology. The product is supplied as frozen cells.\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological source:\u003c\/strong\u003e Mouse (M. musculus)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTissue origin:\u003c\/strong\u003e Liver\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGrowth properties:\u003c\/strong\u003e Adherent, polygonal\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Frozen\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDonor history:\u003c\/strong\u003e Normal tissue\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiosafety level:\u003c\/strong\u003e II\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCulture context:\u003c\/strong\u003e PriCoat™ ECM T25 Flasks (G999) or Applied Cell Extracellular Matrix (G422) are required for cell adhesion to the culture vessels. Complete Hepatocyte Medium Kit (TM159) + 1% Penicillin\/Streptomycin Solution (G255), 37.0°C, 5% CO₂.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eHepatocytes are central to xenobiotic metabolism, intermediary metabolism, protein synthesis, and bile-related functions. Primary hepatocyte models are widely used when physiologic metabolic capacity is important.\u003c\/p\u003e\u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003ePrimary hepatocyte cultures remain important for metabolism, transporter, and toxicity studies requiring liver-relevant function.\u003c\/li\u003e\n\u003cli\u003eLonger-term maintenance and co-culture approaches are used to preserve phenotype for repeated-dose or chronic-exposure designs.\u003c\/li\u003e\n\u003cli\u003eResearchers often profile donor-to-donor variability in metabolism and inducible response pathways.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eEvaluate metabolism, transporter activity, or toxicity responses in liver-relevant in vitro systems.\u003c\/li\u003e\n\u003cli\u003eMeasure inducible gene expression or secreted markers after compound or cytokine treatment.\u003c\/li\u003e\n\u003cli\u003eUse in co-culture workflows to model hepatic crosstalk with stromal or immune cell populations.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eProduct-specific data supplied for this listing\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGrowth Conditions:\u003c\/strong\u003e PriCoat™ ECM T25 Flasks (G999) or Applied Cell Extracellular Matrix (G422) are required for cell adhesion to the culture vessels. Complete Hepatocyte Medium Kit (TM159) + 1% Penicillin\/Streptomycin Solution (G255), 37.0°C, 5% CO₂.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWarranty:\u003c\/strong\u003e abm warrants that cell lines shall be viable upon initiation of culture for a period of thirty (30) days after shipment and that they shall meet the specifications on the applicable abm Material Product Information sheet, certificate of analysis, and\/or catalog description. Such thirty (30) day period is referred to herein as the \"Warranty Period”.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003ePrimary cells can show donor-dependent and passage-dependent variation, so morphology, growth rate, and marker expression should be interpreted in the context of the specific lot and culture history.\u003c\/li\u003e\n\u003cli\u003eAttachment matrix, medium formulation, and gas conditions can materially influence phenotype maintenance and experimental readouts; use the recommended culture system where possible.\u003c\/li\u003e\n\u003cli\u003eCryopreserved recovery conditions matter for viability and downstream behavior. We recommend using serum-free CryoGuard™ Freezing Media (TM078).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"display:none\"\u003eSKU:BHC10901833\u003c\/p\u003e","brand":"Applied Biological Materials (abm) Inc.","offers":[{"title":"5x10\u003csup\u003e5\u003c\/sup\u003e cells \/ 1.0 ml","offer_id":53195751555437,"sku":"T0120","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/niJJv4NyY5oq36BLVK1C04p6vC6919MpFnD85zVf.png?v=1775322478","url":"https:\/\/www.ebiohippo.com\/products\/primary-mouse-cd-1-hepatocytes-plateable-bhc10901833","provider":"BioHippo","version":"1.0","type":"link"}