{"product_id":"prospero-homeobox-protein-1-antibody-prox1-bha17136300","title":"Prospero homeobox protein 1 Antibody \/ PROX1","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003eProspero homeobox protein 1 Antibody \/ PROX1 is a anti-PROX1 Rabbit antibody Recombinant Rabbit Monoclonal clone AOGA-16 supplied in Purified format. Recommended for workflows such as Western blot (WB), IHC-P with listed reactivity in Human. Reported localization: Nuclear.\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTarget:\u003c\/strong\u003e PROX1\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntibody details:\u003c\/strong\u003e Rabbit, Recombinant Rabbit Monoclonal, clone AOGA-16, isotype Rabbit IgG\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Purified\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eApplications (as listed):\u003c\/strong\u003e WB, IHC-P\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eBiological background\u003c\/h2\u003e\u003cdiv\u003ePROX1 is a homeobox transcription factor that orchestrates cell fate programs by binding target DNA motifs and recruiting co-regulators to modulate chromatin accessibility. It is widely studied for its roles in developmental patterning and maintenance of specialized cell identities, particularly within endothelial and neural lineages.\u003cp\u003eIn vascular biology, PROX1 is a master regulator of lymphatic endothelial specification and maintenance, aligning gene expression with signaling inputs that guide vessel identity, remodeling, and tissue fluid balance. Beyond endothelium, PROX1 contributes to organ development and context-dependent transcriptional networks that shape differentiation, metabolism, and tissue architecture.\u003c\/p\u003e\n\u003cp\u003eThe \u003cb\u003eProspero homeobox protein 1 antibody\u003c\/b\u003e enables specific detection of endogenous PROX1 in applications such as immunohistochemistry, immunofluorescence, western blot, and immunoprecipitation. Researchers use the Prospero homeobox protein 1 antibody from\u003c\/p\u003e\n\u003c\/div\u003e\u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eConnecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).\u003c\/li\u003e\n\u003cli\u003eConsidering isoforms and post-translational regulation when interpreting protein-level changes.\u003c\/li\u003e\n\u003cli\u003eComparing results across species and model systems with matched controls.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eWestern blotting:\u003c\/strong\u003e compare relative abundance and activation-state changes across conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmunohistochemistry:\u003c\/strong\u003e map target signal in tissue context and compare regions\/phenotypes.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eInterpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.\u003c\/p\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eSignal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.\u003c\/li\u003e\n\u003cli\u003eSpecies differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eAntibody notes:\u003c\/strong\u003e Monoclonal antibodies provide a defined epitope recognition profile that can support consistent comparisons across experiments.\u003c\/p\u003e\u003c!-- Sources (internal): - UniProt search — UniProt — https:\/\/www.uniprot.org\/uniprotkb?query=PROX1 - NCBI Gene search — NCBI — https:\/\/www.ncbi.nlm.nih.gov\/gene\/?term=PROX1 - Ensembl search — Ensembl — https:\/\/www.ensembl.org\/Multi\/Search\/Results?q=PROX1 - Human Protein Atlas search — HPA — https:\/\/www.proteinatlas.org\/search\/PROX1 - PubMed (review) — NLM — https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=PROX1+review --\u003e","brand":"NSJ Bioreagents","offers":[{"title":"Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg\/ml BSA \/ 100 ul","offer_id":53047324344685,"sku":"RQ8881","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/get_image_1bc72ca5-176a-4338-a8d0-c479f7a1133f.jpg?v=1772019440","url":"https:\/\/www.ebiohippo.com\/products\/prospero-homeobox-protein-1-antibody-prox1-bha17136300","provider":"BioHippo","version":"1.0","type":"link"}