{"product_id":"rab29-antibody-rab7l1-bha17128158","title":"RAB29 Antibody \/ RAB7L1","description":"\u003ch2\u003eOverview\u003c\/h2\u003e \u003cp\u003eRAB29 Antibody \/ RAB7L1 is an antibody targeting \u003cstrong\u003eRAB7L1\u003c\/strong\u003e, raised in \u003cstrong\u003eMouse\u003c\/strong\u003e for protein detection and localization studies where these specifications are required.\u003c\/p\u003e \u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e \u003cul\u003e \u003cli\u003e\n\u003cstrong\u003eTarget:\u003c\/strong\u003e RAB7L1.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eAntibody identity:\u003c\/strong\u003e Polyclonal (rabbit origin); Rabbit Ig.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eConjugate\/label:\u003c\/strong\u003e Unconjugated (affects detection chemistry and multiplex compatibility).\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Purified.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eSpecies reactivity:\u003c\/strong\u003e Human.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eListed applications:\u003c\/strong\u003e WB (refer to on-page specifications for application-specific guidance).\u003c\/li\u003e \u003c\/ul\u003e  \u003ch2\u003eBiological background\u003c\/h2\u003e \u003cp\u003eRAB7L1\/RAB29 is involved in the movement of various molecules within cells, helping to maintain their proper function and organization. It is involvement in the endocytic pathway, where it helps to ensure that molecules are transported to the correct destination within the cell. This process is crucial for maintaining cellular homeostasis and responding to external signals. RAB29 also plays a critical role in autophagy, a process in which cells degrade and recycle damaged or unnecessary components. By regulating the trafficking of autophagosomes, the structures responsible for engulfing and degrading cellular material, RAB29 helps to maintain cell viability and prevent the accumulation of toxic substances. In addition to its roles in cellular trafficking and recycling, RAB29 has also been implicated in various disease processes, including cancer and neurodegenerative disorders.\u003c\/p\u003e \u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e \u003cul\u003e \u003cli\u003eComparative expression profiling across cell types, tissues, or perturbations (e.g., drug treatment, genetic editing, or differentiation).\u003c\/li\u003e \u003cli\u003eSubcellular localization and trafficking studies, including co-localization with pathway markers in microscopy-based assays.\u003c\/li\u003e \u003cli\u003eIntegration of protein-level measurements with transcriptomics or proteomics to relate abundance to regulation and phenotype.\u003c\/li\u003e \u003c\/ul\u003e \u003ch2\u003eCommon research applications\u003c\/h2\u003e \u003cul\u003e \u003cli\u003eWestern blotting: researchers commonly compare relative signal levels across conditions and use appropriate negative\/positive controls for interpretation.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eInterpretation should account for antibody-dependent factors such as epitope accessibility, isoforms, and sample preparation differences across workflows.\u003c\/p\u003e \u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e \u003cul\u003e \u003cli\u003e\n\u003cstrong\u003eIsoforms and PTMs:\u003c\/strong\u003e many targets have multiple isoforms and post-translational modifications that can shift apparent signal or localization; interpret bands\/signals accordingly.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eEpitope context:\u003c\/strong\u003e binding can depend on protein conformation and sample processing; region information in the title\/immunogen can help anticipate what may be detected.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eSpecies differences:\u003c\/strong\u003e predicted or validated reactivity may vary by ortholog sequence and sample context; confirm in your model system.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eControl concepts:\u003c\/strong\u003e include negative controls (no-primary\/isotype), and where possible genetic controls (KO\/KD) or independent antibodies to strengthen conclusions.\u003c\/li\u003e \u003c\/ul\u003e \u003c!-- Sources (internal): - UniProtKB entry O14966 — UniProt — https:\/\/www.uniprot.org\/uniprotkb\/O14966 - Gene search: RAB7L1 — NCBI Gene — https:\/\/www.ncbi.nlm.nih.gov\/gene\/?term=RAB7L1 - Ensembl search: RAB7L1 — Ensembl — https:\/\/www.ensembl.org\/Multi\/Search\/Results?q=RAB7L1 - PubMed search: RAB7L1 antibody — PubMed — https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=RAB7L1+antibody - Reactome search: RAB7L1 — Reactome — https:\/\/reactome.org\/content\/query?q=RAB7L1 --\u003e","brand":"NSJ Bioreagents","offers":[{"title":"In 1X PBS, pH 7.4, with 0.09% sodium azide and 50% glycerol \/ 0.1 ml","offer_id":53046410183021,"sku":"F55095-0.1ML","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/get_image_4ef234aa-ccb9-4d19-85ec-00948fbd42a3.jpg?v=1772000493","url":"https:\/\/www.ebiohippo.com\/products\/rab29-antibody-rab7l1-bha17128158","provider":"BioHippo","version":"1.0","type":"link"}