{"product_id":"rabbit-complement-c3-bhp11006017","title":"Rabbit Complement C3","description":"\u003cp\u003e\u003cstrong\u003eRabbit Complement C3\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eC3 is central to the activation of all 3 pathways of complement activation. Initiation of each pathway generates proteolytic enzyme complexes which binds the target surface. These enzymes cleave a peptide bond in C3 releasing the anaphylatoxin C3a and activating C3b. Most of the C3 activated during complement activation never attaches to the surface due to its thioester reaction with water forming fluid phase C3b which is rapidly inactivated by factors H and I forming iC3b. Surface-bound C3b is necessary in all 3 pathways for efficient activation of C5 and formation of C5b-9 complexes that lyse the target cell membrane.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"10 ug","offer_id":53038180499821,"sku":"pro-2733-10UG","price":385.0,"currency_code":"USD","in_stock":true},{"title":"50 ug","offer_id":53038539866477,"sku":"pro-2733-50UG","price":1045.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53038539899245,"sku":"pro-2733-100UG","price":1650.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-c3-rabbit-PRO-2733.png?v=1782158390","url":"https:\/\/www.ebiohippo.com\/products\/rabbit-complement-c3-bhp11006017","provider":"BioHippo","version":"1.0","type":"link"}