{"product_id":"radicicol-bhb11900008","title":"Radicicol","description":"\u003cp\u003eRadicicol is a macrocyclic antifungal compound that functions as a potent inhibitor of HSP90, a molecular chaperone involved in protein folding and stability. In neuroscience, Radicicol’s ability to bind HSP90 and disrupt its interaction with client proteins offers a mechanism for modulating neurodegenerative disease pathways. It selectively depletes kinases such as Raf and inhibits src-like kinases, contributing to the regulation of cellular stress responses and apoptosis. Radicicol also exhibits anti-angiogenic properties and induces morphological reversion in transformed cells, which may be relevant in neuro-oncology. Its strong binding affinity to HSP90 across species, including yeast and bacterial homologs, underscores its utility in translational research models. By targeting chaperone-mediated proteostasis, Radicicol holds promise for therapeutic intervention in disorders characterized by protein misfolding and aggregation.\u003c\/p\u003e","brand":"StressMarq Biosciences Inc.","offers":[{"title":"1 mg","offer_id":53040944087405,"sku":"SIH-117A","price":141.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/SIH-117_Radicicol_Chemical_Structure.png?v=1771837632","url":"https:\/\/www.ebiohippo.com\/products\/radicicol-bhb11900008","provider":"BioHippo","version":"1.0","type":"link"}