{"product_id":"rat-activated-cdc42-kinase-1-tnk2-elisa-kit-bhe13700218","title":"Rat Activated CDC42 kinase 1 (TNK2) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eRat Activated CDC42 kinase 1 (TNK2) ELISA Kit has high sensitivity and excellent specificity for detection of Rat TNK2. No significant cross-reactivity or interference between Rat TNK2 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eActivated CDC42 kinase 1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain.\u003c\/p\u003e\u003cp\u003eThe protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338583007597,"sku":"KTE100064-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338678198637,"sku":"KTE100064-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338678231405,"sku":"KTE100064-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338678264173,"sku":"KTE100064-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.ebiohippo.com\/products\/rat-activated-cdc42-kinase-1-tnk2-elisa-kit-bhe13700218","provider":"BioHippo","version":"1.0","type":"link"}