{"product_id":"rat-kallikrein-6-klk6-elisa-kit-bhe13700938","title":"Rat Kallikrein-6 (KLK6) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eRat Kallikrein-6 (KLK6) ELISA Kit has high sensitivity and excellent specificity for detection of Rat KLK6. No significant cross-reactivity or interference between Rat KLK6 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eKallikrein 6, also known as Zyme, Neurosin, PRSS9, myelencephalon-specific protease (MSP) and protease M, is a trypsin-like serine proteinase. Kallikrein 6 was originally described from the brain as an enzyme involved in degradation of amyloid plaque protein (APP) and hK6 was thought to be a beta secretase.\u003c\/p\u003e\u003cp\u003eKallikrein 6 was shown to be elevated in the sera patients with Alzheimer’s disease and Parkinson’s disease and in animal models of multiple sclerosis. The neuronal protein alpha-synuclein was shown to be cleaved by hK6, as has APP and hK6 has been implicated in vascular morphogenesis and angiogenesis. MSP has also been shown to rapidly degrade myelin-specific protein, laminin and fibronectin.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338582974829,"sku":"KTE100720-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338676724077,"sku":"KTE100720-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338676756845,"sku":"KTE100720-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338676789613,"sku":"KTE100720-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE100720.png?v=1778954616","url":"https:\/\/www.ebiohippo.com\/products\/rat-kallikrein-6-klk6-elisa-kit-bhe13700938","provider":"BioHippo","version":"1.0","type":"link"}